瑞芬太尼诱发的术后痛感处理指南:病例报告。

Nathan T Smith, Ryan Fernholz, Sanny Juresic
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引用次数: 0

摘要

术后阿片类药物引起的痛觉减退给临床医生处理阿片类药物耐受患者的术后疼痛带来了巨大挑战。Remifentanil 是一种芬太尼类似物,因其良好的药代动力学特征而经常用于麻醉。然而,如病例报告所述,它也可能增加术后痛觉过敏的风险。对于术后痛觉减退情况下的疼痛治疗应采取循序渐进的方式,强调在阿片肽能系统外实现镇痛效果的治疗方案,同时保持阿片类药物的中性平衡。
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Navigating the Postoperative Management of Remifentanil-Induced Hyperalgesia: A Case Report.

Opioid induced hyperalgesia in the postoperative setting presents a significant challenge for clinicians managing postoperative pain in opioid tolerant patients. Remifentanil is a fentanyl analog frequently utilized in anesthesia for its favorable pharmacokinetic profile. However, as described in the case report, it may also increase the risk of postoperative hyperalgesia. Management of postoperative pain in the setting of hyperalgesia should be approached in a stepwise fashion, emphasizing therapy options with analgesic effects achieved outside of the opioidergic system while maintaining a neutral opioid balance.

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来源期刊
CiteScore
1.60
自引率
9.10%
发文量
40
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