[老年黄斑变性--第一部分:病理生理学、分类和诊断]。

IF 0.8 4区 医学 Q4 OPHTHALMOLOGY Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-10 DOI:10.1055/a-2367-8346
Henrik Faatz, Albrecht Peter Lommatzsch
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引用次数: 0

摘要

老年性黄斑变性(AMD)仍然是西方国家老年人中最常见的遗传性疾病。除了临床检查外,荧光素血管造影术、光学相干断层扫描、眼底自发荧光和眼底摄影等多模态成像技术对于正确诊断和分类至关重要。这对于晚期疾病的风险评估尤为重要。自从引入了针对血管内皮生长因子(VEGF)的玻璃体内疗法以来,新生血管性黄斑变性的治疗选择大大增加,患者在维持视力方面的预后也有所改善。人们希望开发出更强效、更持久的药物,并希望治疗地理萎缩的药物获得批准。因此,为患者做出快速、正确的诊断至关重要。本文将概述 AMD 的病理生理学、分类和诊断。
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[Age-related macular degeneration - Part 1: Pathophysiology, classification and diagnostic].

Age-related macular degeneration (AMD) continues to be the most common hereditary disease among older people in the western world. In addition to the clinical examination, multimodal imaging with fluorescein angiography, optical coherence tomography, fundus autofluorescence and fundus photography are crucial for the correct diagnosis and classification. This is particularly important with regard to risk assessment for the development of a late form of the disease. Since the introduction of intravitreal therapy against vascular endothelial growth factor (VEGF), the treatment options for neovascular AMD have increased significantly and the prognosis for patients in terms of maintaining their vision has improved. The hope is to develop stronger and longer-lasting drugs and also to obtain approval for drugs to treat geographic atrophy. It is therefore of great importance to be able to make a quick and correct diagnosis for patients. In this paper we want to present an overview of the pathophysiology, classification and diagnosis of AMD.

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CiteScore
1.30
自引率
0.00%
发文量
235
审稿时长
4-8 weeks
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