[放射成像在肝细胞癌精确诊断和治疗中的应用研究进展和前景]。

J Zhou, T W Chen, D J Guo
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引用次数: 0

摘要

肝细胞癌(HCC)是一种高度异质性的恶性肿瘤,复发率高,五年生存率低,已成为中国重大公共卫生问题之一。目前,HCC 是唯一一种无需术前病理确诊,仅凭流行病学史和典型影像学特征即可诊断的实体瘤。近年来,在精准医学的背景下,HCC影像诊断的范式已从解剖转向功能、从宏观转向微观、从诊断转向预测,使得从定性和定量的影像学角度研究HCC基因及其代谢规律等微观过程成为可能,从而为阐明HCC的发生、发展和临床治疗决策提供更准确的生物学和影像学信息。本文回顾了近年来HCC影像学的研究进展,展示了影像学在HCC精准诊断和治疗的纵向随访中的横向快速发展和巨大潜力。同时,也提出了目前 HCC 影像学研究的不足之处,并展望了未来的发展方向,以期更精准地应用于临床决策支持系统。
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[Research progress and prospects of the application of radiographic imaging in the precise diagnosis and treatment of hepatocellular carcinoma].

Hepatocellular carcinoma (HCC) is a highly heterogeneous kind of malignant tumor with a high recurrence rate and low five-year survival rate, which has become one of the major public health issues in China. Currently, HCC is the only solid tumor that can be solely diagnosed based on epidemiological history and typical imaging features without preoperative pathological confirmation. The paradigm for HCC imaging diagnosis has shifted in recent years from anatomy to function, from macroscopic to microscopic, and from diagnosis to prediction in the context of precision medicine, making it possible to study the microscopic processes such as HCC genes and their metabolic laws from the perspective of qualitative and quantitative imaging, thereby providing more accurate biological and imaging information for elucidating the occurrence, development, and clinical treatment decisions of HCC.This paper reviews the research progress of HCC imaging in recent years, demonstrating the rapid horizontal development and enormous potential of imaging in the vertical follow-up of HCC precision diagnosis and treatment. Simultaneously, it also puts forward the shortcomings of current HCC imaging research and looks forward to future development directions in order to be more accurately used in clinical decision support systems.

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来源期刊
中华肝脏病杂志
中华肝脏病杂志 Medicine-Medicine (all)
CiteScore
1.20
自引率
0.00%
发文量
7574
期刊介绍:
期刊最新文献
[The Research and Application Progress of Heterologous Liver Transplantation]. [The nomogram model and its value study of Gd-EOB-DTPA enhanced MRI for preoperative diagnosis of proliferative hepatocellular carcinoma]. [Excerpt from the 2023 European Association for the Study of the Liver practice guidelines: prevention, diagnosis, and treatment of intrahepatic cholangiocarcinoma]. [Rifaximin curative effect and mechanism on monocrotaline-induced hepatic sinusoidal obstruction syndrome in mice]. [A case of Wilson's disease misdiagnosed as autoimmune hepatitis and literature review].
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