肾移植候选者和接受者的结核病。

Pallavi Prasad, Sourabh Sharma, Subashri Mohanasundaram, Anupam Agarwal, Himanshu Verma
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引用次数: 0

摘要

结核病(TB)是全球传染病死亡和发病的主要原因,仅次于 2019 年的冠状病毒病。与普通人群相比,慢性肾病患者和肾移植受者患结核病的风险更高。由于与肺结核相似,活动性肺结核在这类人群中很难诊断。所有移植候选者都应接受结核潜伏感染筛查,并接受结核预防治疗。移植前或移植后出现活动性肺结核的患者应在建议的疗程内接受多药联合抗结核治疗,并根据肾小球滤过率调整最佳剂量。
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Tuberculosis in kidney transplant candidates and recipients.

Tuberculosis (TB) is the leading cause of infectious mortality and morbidity in the world, second only to coronavirus disease 2019. Patients with chronic kidney disease and kidney transplant recipients are at a higher risk of developing TB than the general population. Active TB is difficult to diagnose in this population due to close mimics. All transplant candidates should be screened for latent TB infection and given TB prophylaxis. Patients who develop active TB pre- or post-transplantation should receive multidrug combination therapy of antitubercular therapy for the recommended duration with optimal dose modification as per glomerular filtration rate.

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