{"title":"[咽喉炎并发化脓性并发症]。","authors":"Ayla Koçak, Christine Hansen-Wester, Annegret Krenz-Weinreich, Malte Milkau","doi":"10.1007/s00108-024-01793-1","DOIUrl":null,"url":null,"abstract":"<p><p>A young man presented with exertional dyspnea and thoracic pain following pharyngitis. The findings included pulmonary melting, left-sided pleural empyema and spondylitis. Cultures for detection of the pathogen were negative and sequencing for bacterial DNA was additionally carried out resulting in detection of Fusobacterium necrophorum that is typical for oropharyngeal infections. Furthermore, environmental diagnostics revealed two infected molars as a possible source of the infection and a jugular vein thrombosis. The results were compatible with Lemierre syndrome. This case highlights the potential of molecular diagnostics of pathogens.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"129-131"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Sore throat with septic complications].\",\"authors\":\"Ayla Koçak, Christine Hansen-Wester, Annegret Krenz-Weinreich, Malte Milkau\",\"doi\":\"10.1007/s00108-024-01793-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A young man presented with exertional dyspnea and thoracic pain following pharyngitis. The findings included pulmonary melting, left-sided pleural empyema and spondylitis. Cultures for detection of the pathogen were negative and sequencing for bacterial DNA was additionally carried out resulting in detection of Fusobacterium necrophorum that is typical for oropharyngeal infections. Furthermore, environmental diagnostics revealed two infected molars as a possible source of the infection and a jugular vein thrombosis. The results were compatible with Lemierre syndrome. This case highlights the potential of molecular diagnostics of pathogens.</p>\",\"PeriodicalId\":73385,\"journal\":{\"name\":\"Innere Medizin (Heidelberg, Germany)\",\"volume\":\" \",\"pages\":\"129-131\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Innere Medizin (Heidelberg, Germany)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00108-024-01793-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Innere Medizin (Heidelberg, Germany)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00108-024-01793-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/24 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
一名年轻男子因咽炎出现劳力性呼吸困难和胸痛。检查结果包括肺融化、左侧胸腔积液和脊柱炎。病原体的培养检测结果为阴性,另外还进行了细菌 DNA 测序,结果检测出了典型的口咽部感染的坏死镰刀菌。此外,环境诊断显示,两颗受感染的臼齿可能是感染源,同时还发现了颈静脉血栓。结果与莱米埃尔综合征相符。该病例凸显了病原体分子诊断的潜力。
A young man presented with exertional dyspnea and thoracic pain following pharyngitis. The findings included pulmonary melting, left-sided pleural empyema and spondylitis. Cultures for detection of the pathogen were negative and sequencing for bacterial DNA was additionally carried out resulting in detection of Fusobacterium necrophorum that is typical for oropharyngeal infections. Furthermore, environmental diagnostics revealed two infected molars as a possible source of the infection and a jugular vein thrombosis. The results were compatible with Lemierre syndrome. This case highlights the potential of molecular diagnostics of pathogens.