Daniel Casey, Laura Diaz-Garcia, Mincen Yu, Kang Lan Tee, Tuck Seng Wong
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引用次数: 0
摘要
合成生物学领域不断扩大,要求微生物底盘多样化,以加快从依赖化石燃料的经济向可持续生物经济过渡。仅仅依靠大肠杆菌和酿酒酵母等成熟的模式生物可能不足以推动生物技术所需的巨大进步。在这种情况下,Cupriavidus necator(一种用途极为广泛的微生物)已成为工业生物制造领域实现变革性突破的潜在催化剂。本书的这一章节深入回顾了过去十年中C. necator所取得的显著技术进步,特别关注分子生物学工具、代谢工程和创新发酵策略等领域。通过这一探索,我们旨在阐明 C. necator 在塑造可持续生物加工和生物产品开发的未来方面所发挥的关键作用。
From Knallgas Bacterium to Promising Biomanufacturing Host: The Evolution of Cupriavidus necator.
The expanding field of synthetic biology requires diversification of microbial chassis to expedite the transition from a fossil fuel-dependent economy to a sustainable bioeconomy. Relying exclusively on established model organisms such as Escherichia coli and Saccharomyces cerevisiae may not suffice to drive the profound advancements needed in biotechnology. In this context, Cupriavidus necator, an extraordinarily versatile microorganism, has emerged as a potential catalyst for transformative breakthroughs in industrial biomanufacturing. This comprehensive book chapter offers an in-depth review of the remarkable technological progress achieved by C. necator in the past decade, with a specific focus on the fields of molecular biology tools, metabolic engineering, and innovative fermentation strategies. Through this exploration, we aim to shed light on the pivotal role of C. necator in shaping the future of sustainable bioprocessing and bioproduct development.
期刊介绍:
Advances in Biochemical Engineering/Biotechnology reviews actual trends in modern biotechnology. Its aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required for chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. They give the state-of-the-art of a topic in a comprehensive way thus being a valuable source for the next 3 - 5 years. It also discusses new discoveries and applications.