与胸骨后即刻植入假体的乳房重建相比,胸骨前植入假体是否会延迟辅助治疗?回顾性分析。

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引用次数: 0

摘要

背景:与胸骨后(RP)乳房重建相比,胸骨前(PP)即刻植入假体乳房重建(IBBR)越来越受欢迎。本研究比较了PP或RP IBBR术后不同辅助治疗(AT)的用药时机:对2018年1月至2023年12月期间接受乳房切除术和IBBR的患者进行了单中心回顾性分析。收集并分析了术前特征、乳房切除手术类型、PP或RP植入物放置、术后结果、AT类型以及手术与AT用药之间的时间:结果:共纳入 167 名患者(206 个乳房)。结果:共纳入 167 例患者(206 个乳房),其中 123 例接受了 PP IBBR,44 例接受了 RP IBBR。PP组(45.7天,SD 39.3)与RP组(37.4天,SD 33.1)相比,手术与首次给药之间的平均时间相似(P值为0.2100)。内分泌治疗(ET)、化疗(CT)或放疗(RT)的开始时间在 PP 组和 RP 组之间没有发现明显差异。有血清肿的患者开始 CT 的时间(83.67 天,SD 123.7)晚于无血清肿的患者(42.1 天,SD 29.7)(P 值 0.0298):与RP IBBR相比,PP IBBR从手术到首次使用AT的平均时间相似。在所有人群中,术后血清肿与 CT 延误有关。
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Does prepectoral placement delay adjuvant therapies compared to retropectoral immediate implant-based breast reconstruction? A retrospective analysis

Background

Prepectoral (PP) immediate implant-based breast reconstruction (IBBR) is becoming increasingly popular compared to retropectoral (RP) reconstruction. This study compares the timing of administration of different adjuvant therapy (ATs) after PP or RP IBBR.

Patients and methods

A monocentric retrospective analysis was conducted on patients undergoing mastectomy and IBBR from January 2018 to December 2023. Preoperative characteristics, mastectomy procedure type, PP or RP implant placement, postoperative outcomes, AT type, and time between surgery and AT administration were collected and analyzed.

Results

167 patients (206 breasts) were included. 123 underwent PP IBBR and 44 RP IBBR. The mean time between surgery and first AT administration was similar in the PP group (45.7 days, SD 39.3) compared to the RP group (37.4 days, SD 33.1) (p-value 0.2100). No significant differences were found in the timing of endocrine therapy (ET), chemotherapy (CT), or radiotherapy (RT) initiation between the PP and RP groups. Patients with seroma had a delayed initiation of CT (83.67 days, SD 123.7) versus those without seroma (42.1 days, SD 29.7) (p-value 0.0298).

Conclusions

The average time between surgery and administration of the first AT following PP IBBR was similar compared to RP IBBR. Postoperative seromas were associated with delayed CT in the overall population.
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来源期刊
CiteScore
3.10
自引率
11.10%
发文量
578
审稿时长
3.5 months
期刊介绍: JPRAS An International Journal of Surgical Reconstruction is one of the world''s leading international journals, covering all the reconstructive and aesthetic aspects of plastic surgery. The journal presents the latest surgical procedures with audit and outcome studies of new and established techniques in plastic surgery including: cleft lip and palate and other heads and neck surgery, hand surgery, lower limb trauma, burns, skin cancer, breast surgery and aesthetic surgery.
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