{"title":"剪接体因子和 RNA 螺旋酶 Brr2a 在 miRNA 生产中发挥着重要作用","authors":"","doi":"10.1038/s41477-024-01822-9","DOIUrl":null,"url":null,"abstract":"The secondary structure of pri-miRNAs determines the efficiency and accuracy of miRNA production. RNA helicase Brr2a, a key component of spliceosomes in Arabidopsis, can interact with the pri-miRNA processing machinery component HYL1 and fine-tune the structures of pri-miRNAs to enhance miRNA production, whether the pri-miRNAs contain introns or not.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 10","pages":"1444-1445"},"PeriodicalIF":15.8000,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The spliceosome factor and RNA helicase Brr2a moonlights in miRNA production\",\"authors\":\"\",\"doi\":\"10.1038/s41477-024-01822-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The secondary structure of pri-miRNAs determines the efficiency and accuracy of miRNA production. RNA helicase Brr2a, a key component of spliceosomes in Arabidopsis, can interact with the pri-miRNA processing machinery component HYL1 and fine-tune the structures of pri-miRNAs to enhance miRNA production, whether the pri-miRNAs contain introns or not.\",\"PeriodicalId\":18904,\"journal\":{\"name\":\"Nature Plants\",\"volume\":\"10 10\",\"pages\":\"1444-1445\"},\"PeriodicalIF\":15.8000,\"publicationDate\":\"2024-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Plants\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.nature.com/articles/s41477-024-01822-9\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Plants","FirstCategoryId":"99","ListUrlMain":"https://www.nature.com/articles/s41477-024-01822-9","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
The spliceosome factor and RNA helicase Brr2a moonlights in miRNA production
The secondary structure of pri-miRNAs determines the efficiency and accuracy of miRNA production. RNA helicase Brr2a, a key component of spliceosomes in Arabidopsis, can interact with the pri-miRNA processing machinery component HYL1 and fine-tune the structures of pri-miRNAs to enhance miRNA production, whether the pri-miRNAs contain introns or not.
期刊介绍：
Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.
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