Andrzej Hasiec, Mariusz Kruk, Cezary Kępka, Grzegorz Warmiński, Ilona Kowalik, Maria Bilińska, Łukasz Szumowski
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Patients with AF were older (61.8 [10.4] years vs. 58.3 [9.2] years; P = 0.005), had an enlarged left atrium in the anteroposterior dimension (38.2 [7.2] mm vs. 34.4 [5.4] mm; P < 0.001), and had a widened interventricular septum (12.3 [2.0] mm vs. 11.0 [2.1] mm; P < 0.001). We also found a significant correlation between the occurrence of AF in patients with coronary atherosclerotic lesions and with increased thickness of the interventricular septum relative to the posterior wall of the left ventricle (P = 0.017).</p><p><strong>Conclusions: </strong>Our data indicate an association between coronary atherosclerosis and the greater risk of AF in patients with increased thickness of the interventricular septum relative to the posterior wall of the left ventricle. 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引用次数: 0
摘要
背景:目的:评估经冠状动脉计算机断层扫描(CCTA)证实有冠状动脉粥样硬化的患者新发房颤的风险和预测因素:我们纳入了连续转诊接受 CCTA 的患者,这些患者在 10 年内曾被观察和诊断为新发房颤:在参与研究的 549 名患者中,208 人(37.9%)被诊断为冠状动脉粥样硬化病变,63 人(11.5%)在 10 年的观察期间发展为房颤。心房颤动患者年龄较大(61.8 [10.4] 岁 vs. 58.3 [9.2] 岁;P = 0.005),左心房前后径增大(38.2 [7.2] mm vs. 34.4 [5.4] mm;P < 0.001),室间隔增宽(12.3 [2.0] mm vs. 11.0 [2.1] mm;P < 0.001)。我们还发现,冠状动脉粥样硬化病变患者房颤的发生与室间隔相对于左心室后壁的厚度增加有明显相关性(P = 0.017):我们的数据表明,冠状动脉粥样硬化与室间隔相对于左心室后壁厚度增加的患者发生房颤的风险更大有关。这一发现表明,通过使用 CCTA,我们可以预测哪些患者罹患房颤的风险更高。
Evaluating the effect of coronary atherosclerosis on the occurrence of atrial fibrillation through coronary computed tomography angiography.
Background: The direct impact of atherosclerotic lesions in coronary vessels on the occurrence of atrial fibrillation (AF) in patients without a history of acute myocardial ischemia, previous myocardial infarction, or revascularization procedures remains largely unknown.
Aims: To assess the risk and predictors of new-onset AF in patients with coronary atherosclerosis confirmed by coronary computed tomography angiography (CCTA).
Methods: We included consecutive patients referred for CCTA who had been observed and diagnosed with new-onset AF over 10 years.
Results: Of the 549 patients enrolled in the study, 208 (37.9%) were diagnosed with atherosclerotic lesions in the coronary vessels and 63 (11.5%) developed AF during the 10 years of observation. Patients with AF were older (61.8 [10.4] years vs. 58.3 [9.2] years; P = 0.005), had an enlarged left atrium in the anteroposterior dimension (38.2 [7.2] mm vs. 34.4 [5.4] mm; P < 0.001), and had a widened interventricular septum (12.3 [2.0] mm vs. 11.0 [2.1] mm; P < 0.001). We also found a significant correlation between the occurrence of AF in patients with coronary atherosclerotic lesions and with increased thickness of the interventricular septum relative to the posterior wall of the left ventricle (P = 0.017).
Conclusions: Our data indicate an association between coronary atherosclerosis and the greater risk of AF in patients with increased thickness of the interventricular septum relative to the posterior wall of the left ventricle. This finding suggests that by using CCTA we can predict which patients are at higher risk of developing AF.
期刊介绍:
Kardiologia Polska (Kardiol Pol, Polish Heart Journal) is the official peer-reviewed journal of the Polish Cardiac Society (PTK, Polskie Towarzystwo Kardiologiczne) published monthly since 1957. It aims to provide a platform for sharing knowledge in cardiology, from basic science to translational and clinical research on cardiovascular diseases.