Michelle Tran, Chun Anna Xu, Jonathan Wilson, Rasheeda Hall, Patti L Ephraim, Tariq Shafi, Daniel E Weiner, Benjamin A Goldstein, Julia J Scialla
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引用次数: 0
摘要
背景：选择明智 "运动建议对接受透析的患者进行个体化的癌症筛查。我们的目的是根据肾移植等待者名单和五年生存概率评估接受维持性血液透析（HD）患者的乳腺癌和前列腺癌筛查情况：我们利用具有全国代表性的血液透析患者群体开展了一项回顾性队列研究。研究对象包括：2003-2018 年期间每年接受 HD 治疗的患者，医疗保险（Medicare）作为主要支付方的时间≥1 年，年龄在 50-69 岁之间。队列分为预后组和癌症筛查组。在预后组中使用逻辑回归建立了五年生存率模型。在癌症筛查组中生成了五年生存概率，排除了曾患乳腺癌或前列腺癌的患者，并对下一年的筛查情况进行了评估：160,537名患者为癌症筛查集贡献了356,165人年（59%的人年由男性贡献，年龄中位数为60岁）。与 50%的基准率（如每隔一年进行一次乳房 X 光检查）相比，42% 的候诊女性年接受了乳房 X 光检查。总体而言，17%的非候诊女性接受了筛查（在五年生存概率大于 50% 的女性中，20% 接受了筛查；在五年生存概率为 50% 的女性中，8% 接受了筛查；在五年生存概率为 1% 的女性中，1% 接受了筛查）：预测存活率较高的患者接受癌症筛查的比例较高，这表明医疗服务提供者会考虑患者的预期寿命。然而，与等候名单上的患者相比，五年生存概率高的非等候名单上的患者接受筛查的可能性较低。可能需要采取干预措施来缩小这一筛查差距。
期刊介绍：
The Clinical Journal of the American Society of Nephrology strives to establish itself as the foremost authority in communicating and influencing advances in clinical nephrology by (1) swiftly and effectively disseminating pivotal developments in clinical and translational research in nephrology, encompassing innovations in research methods and care delivery; (2) providing context for these advances in relation to future research directions and patient care; and (3) becoming a key voice on issues with potential implications for the clinical practice of nephrology, particularly within the United States. Original manuscript topics cover a range of areas, including Acid/Base and Electrolyte Disorders, Acute Kidney Injury and ICU Nephrology, Chronic Kidney Disease, Clinical Nephrology, Cystic Kidney Disease, Diabetes and the Kidney, Genetics, Geriatric and Palliative Nephrology, Glomerular and Tubulointerstitial Diseases, Hypertension, Maintenance Dialysis, Mineral Metabolism, Nephrolithiasis, and Transplantation.
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