病例报告:重申组织活检在肺结核诊断中的重要性:从一例并发霍奇金淋巴瘤的小儿肺结核病例中汲取的教训。

IF 2.1 3区 医学 Q2 PEDIATRICS Frontiers in Pediatrics Pub Date : 2024-10-03 eCollection Date: 2024-01-01 DOI:10.3389/fped.2024.1454657
Yonghan Luo, Xiaotao Yang, Jun Zhou, Shuangqiong Pu, Yanchun Wang
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引用次数: 0

摘要

儿童结核感染的临床症状并不典型,需要与多种疾病相鉴别,肿瘤就是其中之一。我们介绍了一例颈部淋巴结肿大的患儿,其纯化蛋白衍生物(PPD)和干扰素-γ释放测定结果均为阳性,最终通过颈部淋巴结活检确诊为霍奇金淋巴瘤。我们从这个病例中吸取了一些教训:首先,病理活检仍是诊断结核病的 "金标准"。其次,肿块细针穿刺活检取样存在局限性,最好采用手术方法进行淋巴结活检,以获取更大的组织,提高结核病检测灵敏度。
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Case Report: Reiterating the importance of tissue biopsy in the diagnosis of tuberculosis: lessons from a case of pediatric pulmonary tuberculosis complicated by Hodgkin's lymphoma.

The clinical symptoms of tuberculosis infection in children are not typical and need to be distinguished from many diseases, and the tumor is one of them. We present a case of cervical lymphadenopathy in a child with positive purified protein derivative (PPD) and Interferon-Gamma Release Assay results, ultimately diagnosed with Hodgkin's lymphoma via cervical lymph node biopsy. We learned some lessons from the case: First, Pathological biopsy remains the "gold standard" for diagnosing tuberculosis. Second, there are limitations of sampling in lump fine needle aspiration biopsy, surgical methods for lymph node are preferred to obtain larger tissues and improve tuberculosis detection sensitivity.

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来源期刊
Frontiers in Pediatrics
Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.60
自引率
7.70%
发文量
2132
审稿时长
14 weeks
期刊介绍: Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
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