二胎流产后的妊娠结局:药物流产与手术流产的比较。一项历史性队列研究。

IF 2.6 3区 医学 Q2 OBSTETRICS & GYNECOLOGY International Journal of Gynecology & Obstetrics Pub Date : 2024-10-19 DOI:10.1002/ijgo.15958
Hanaa Abokaf, Elena Korytnikova, Shimrit Yaniv-Salem, Ilana Shoham-Vardi, Ruslan Sergienko, Boaz Sheizaf, Adi Y Weintraub
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引用次数: 0

摘要

目的比较根据流产方式分层的第二胎流产后妊娠的围产期结局:方法:在一家三甲医院进行了一项历史性队列研究,研究对象包括在 12+0 到 24+0 周之间进行第二胎流产的妇女,以及随后在 3-60 个月内有记录的妊娠。数据收集自住院和围产期数据库。构建了综合结果变量,并使用多变量逻辑回归分析了相关性,同时对混杂因素进行了调整:在符合纳入标准的 771 名妇女中,83% 进行了手术流产,17% 进行了药物流产。与手术流产相比,药物流产与胎盘相关的妊娠并发症发生率更高。在其他围产期结果方面未发现明显差异:这项研究强调了人工流产方法对后续妊娠结局的潜在影响,尤其是与胎盘相关的并发症。这强调了在向妇女提供有关后续妊娠潜在风险的咨询时考虑第二孕期人工流产方法的重要性。第二胎人工流产后的不良妊娠结局与药物流产方法有关,因此在临床实践中需要进一步研究和仔细咨询。
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Pregnancy outcomes following second-trimester abortions: A comparison between medical and surgical management. A historic cohort study.

Objective: To compare perinatal outcomes in subsequent pregnancies following second-trimester abortions, stratified by the method of abortion.

Methods: A historic cohort study was conducted in a single tertiary hospital, including women who had second-trimester abortions between 12+0 and 24+0 weeks and subsequent documented pregnancies within 3-60 months. Data were collected from hospitalization and perinatal databases. Composite outcome variables were constructed, and multivariable logistic regression was used to analyze associations, adjusting for confounders.

Results: Among 771 women meeting the inclusion criteria, 83% had surgical abortions and 17% had medical abortions. Medical abortion was associated with a higher incidence of placenta-associated pregnancy complications compared with surgical abortion. No significant differences were found in other perinatal outcomes.

Conclusion: The study highlights the potential influence of the abortion method on subsequent pregnancy outcomes, particularly regarding placenta-associated complications. This underscores the importance of considering the method of second-trimester abortion in counseling women regarding potential risks to subsequent pregnancies. Adverse outcomes in subsequent pregnancies following second-trimester abortion were associated with the medical method of abortion, warranting further research and careful counseling in clinical practice.

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来源期刊
CiteScore
5.80
自引率
2.60%
发文量
493
审稿时长
3-6 weeks
期刊介绍: The International Journal of Gynecology & Obstetrics publishes articles on all aspects of basic and clinical research in the fields of obstetrics and gynecology and related subjects, with emphasis on matters of worldwide interest.
期刊最新文献
Letter to the editor: Clinician perspectives on hysterectomy versus uterine preservation in pelvic organ prolapse surgery: A systematic review and meta-analysis. Oncological safety of fertility preservation treatment in ovarian cancer: A Spanish multicenter study. Proposal for a new classification of intrauterine adhesions by sites. Retraction: Multicenter Randomized Controlled Trial Assessing the Impact of a Cervical Traction Maneuver (Amr's Maneuver) on the Incidence of Postpartum Hemorrhage. Retracted: Safety and efficacy of titrated oral misoprostol solution versus vaginal dinoprostone for induction of labor: A single-center randomized control trial.
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