转录记忆的形成:转录因子与抑制染色质之间的斗争

IF 7.7 Cell systems Pub Date : 2024-10-16 DOI:10.1016/j.cels.2024.09.008
Zuodong Zhao, Bing Zhu
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引用次数: 0

摘要

转录记忆使细胞能够以更快、更强和更灵敏的方式对以前经历过的信号做出反应。利用合成生物学方法,Fan 及其同事发现了转录因子和抑制性染色质在巩固转录记忆过程中的关键相互作用。
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Transcriptional memory formation: Battles between transcription factors and repressive chromatin.

Transcriptional memory allows cells to respond to previously experienced signals in a faster, stronger, and more sensitive manner. Using synthetic biology approaches, Fan and colleagues uncovered the critical interplays between transcription factors and repressive chromatin in consolidating transcriptional memory.

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