治疗一名无法手术的肿瘤性钙化伴终末期肾病患者:病例报告。

Sarah K Couser, Donna J Claes, Sydney Huesman, David K Hooper
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摘要

我们描述了一例严重的无症状肿瘤性钙化病例,患者是一名年轻男性,因抗中性粒细胞胞浆抗体相关性血管炎继发终末期肾病,并伴有长期高磷血症和继发性甲状旁腺功能亢进,同时已接受腹膜透析数年。为了治疗无法手术的肿瘤性钙化症,他使用了静脉注射硫代硫酸钠、每周五次的血液透析优化清除率以及透析内营养。3 个月后,他的钙化肿块明显缩小,疼痛也有所改善。随后,他接受了活体肾移植。
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Treatment of a patient with inoperable tumoral calcinosis associated with end stage kidney disease: A case report.

We describe a case of severe symptomatic tumoral calcinosis in a young man with end stage kidney disease secondary to antineutrophil cytoplasmic antibodies-associated vasculitis with longstanding hyperphosphatemia and secondary hyperparathyroidism while on several years of peritoneal dialysis. The use of intravenous sodium thiosulfate, optimization of clearance with five times weekly hemodialysis, and intradialytic nutrition were used to treat his inoperable tumoral calcinosis. Over 3 months, he had a remarkable reduction in the size of his calcified masses and associated improvement in pain. He subsequently received a living donor kidney transplant.

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