中国胰腺癌诊治概况:中国胰腺癌诊治概况:现状与前景

Sakarie Mustafe Hidig
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摘要

这篇全面的文献综述旨在总结有关胰腺癌的病因、诊断和治疗的最新研究成果,并鼓励对这种研究不足的恶性肿瘤进行更多的调查。胰腺癌在中国是一个重要的公共卫生问题,每年的死亡率几乎与发病率相当。胰腺癌在农村地区发病率较高,预后较差。数据收集自以下数据库:Pub Med、Cross ref、Science Direct、Scopus 和 Google Scholar,我们查阅了 2018 年至 2023 年发表的关于中国胰腺癌年发病率为 5.1%,仅有 5-7% 的患者完全治愈的文章。预后极差,1 年生存率为 8%,5 年生存率为 3%。胰腺癌没有特异的临床表现和肿瘤标志物,其特征与吸烟、饮酒、慢性胰腺炎、微生物代谢异常、血型、血糖和血脂等高危因素并不典型。为了提高发现率和生存率,胰腺癌必须尽早诊断。然而,肿瘤标志物的特异性较低,需要进行更多的研究。未来的治疗策略可能包括免疫疗法和无微生物系统,预计它们将为延长胰腺癌患者的生命提供有趣的临床应用。最后,我们建议采取措施改善中国胰腺癌患者的健康状况。
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An Overview of Pancreatic Cancer Diagnosis and Treatment in China: Current Landscape and Future Prospects.

This comprehensive literature review is to summarize the most recent findings regarding the causes, diagnosis, and treatments of pancreatic cancer and to encourage additional investigation into this under-researched malignant tumor. Pancreatic cancer is a significant public health issue in China, with annual mortality rates almost equal to incidence rates. The disease is more prevalent in rural areas and has a poor prognosis. The data was collected from the following databases: Pub Med, Cross ref, Science Direct, Scopus, and Google Scholar we reviewed published articles from 2018 to 2023 on the annual incidence of pancreatic cancer in China is 5.1%, with only 5-7% of patients completely cured. The prognosis is extremely poor, with a 1-year survival rate of 8% and a 5-year survival rate of 3%. Pancreatic cancer has no specific clinical manifestations or tumor markers, and its characteristics are not typical of high-risk factors including smoking, alcohol, chronic pancreatitis, abnormal microorganism metabolism, blood type, and glucose and lipid levels. For increased detection and survival rates, pancreatic cancer must be diagnosed as early as possible. However, the low specificity of tumor markers calls for more study. Future treatment strategies could include immunotherapy and a microbiology-free system, and it's anticipated that they'll offer intriguing clinical applications for extending patients' lives with pancreatic cancer. Finally, we suggest measures to improve the health outcomes of pancreatic cancer patients in China.

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