口腔鳞状细胞癌(OSCC)中的外泌体之旅

Raman Dineja, R. Ashwini
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引用次数: 0

摘要

"细胞外囊泡 "是细胞外囊泡中最重要的种类之一。它们有助于细胞内的交流。外泌体的末端参与免疫调节、基质适应和多种生物事件。口腔鳞状细胞癌(OSCC)被认为是世界上第二常见的癌症。口腔癌只有在晚期才会被发现,因此预后很差。如今,许多研究项目都在进行口腔鳞状细胞癌的早期检测和诊断。在这些研究中,外泌体在检测口腔鳞状细胞癌方面发挥着至关重要的作用。我们在PubMed上搜索了2005年1月至2024年3月期间发表的有关外泌体在口腔鳞状细胞癌(OSCC)中作用的英文全文论文。本综述旨在及时了解外泌体在OSCC各方面的应用研究。这篇综述有助于回顾每年利用外泌体在OSCC的诊断、治疗计划和预后方面取得的成就。
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Journey of Exosomes in Oral Squamous Cell Carcinoma (OSCC)
“EXOSOMES” are one of the most important varieties of extracellular vesicles. They help in communication within the cell. The end version of exosomes involves in immune-modulation, stromal adaptation, and multiple biological events. Oral squamous cell carcinoma (OSCC) is considered as second most common cancer in the world. Detection of oral carcinoma happens only during the end stage which makes very poor prognosis of the condition. Now a days multiple research projects are conducted to detect and diagnose the oral squamous cell carcinoma during its early stage. In these researches exosomes play a vital role in detecting the OSCC. A PubMed search was performed for English-language, full-text available papers published from January 2005 to March 2024, focusing on exosomes role in Oral squamous cell carcinoma (OSCC). This review is done to understand the timely research where exosomes are used in various aspect in terms of OSCC. This review help to recall the yearly achievement in the diagnosis, treatment planning, prognosis of OSCC by utilising the exosomes.
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