IF 2.3 3区 生物学Q2 MULTIDISCIPLINARY SCIENCESPeerJPub Date : 2024-10-29eCollection Date: 2024-01-01DOI:10.7717/peerj.18207
Yuan Li, Ming Zhao, Xuemei Li, Tiejuan Liu, Lin Zheng, Deyu Hu, Tongyan Liu, Lingyun Zhou
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引用次数: 0
摘要
背景:通过荟萃分析探讨动脉瘤手术后眼运动神经麻痹(ONP)恢复的风险因素:方法:在PubMed、Embase、web of science、Cochrane library、中国知网、万方、VIP等数据库中检索动脉瘤术后眼球运动神经麻痹恢复风险因素的病例对照或队列研究,截止日期为2024年2月14日,使用Stata 15对数据进行分析:荟萃分析结果表明,性别(OR = 0.75,95% CI [0.51-1.10])、年龄(OR = 1.00,95% CI [0.93-1.07])、动脉瘤大小(OR = 0.85,95% CI [-0.71-1.01])、治疗时间(OR = 1.01,95% CI [0.91-1.13])不是动脉瘤术后运动神经麻痹恢复的危险因素。术前完全ONP(OR = 2.27,95% CI [1.07-4.81])、手术(OR = 9.88,95% CI [2.53-38.57])、蛛网膜下腔出血(OR = 1.29,95% CI [1.06-1.56])是动脉瘤术后运动神经麻痹恢复的危险因素:根据我们纳入的研究结果,我们发现手术前完全ONP会导致患者恢复较差,但术后合并蛛网膜下腔出血的患者恢复较好。
Risk factors for recovery from oculomotor nerve palsy after aneurysm surgery: a meta-analysis.
Background: Risk factors for recovery from oculomotor nerve palsy (ONP) after aneurysm surgery explored by meta-analysis.
Methods: The PubMed, Embase, web of science, Cochrane library, China Knowledge, Wan fang, and VIP databases were searched for case-control or cohort studies on risk factors of oculomotor nerve palsy recovery after aneurysm surgery, with a cut-off date of 14 February 2024, and data were analyzed using Stata 15.
Result: A total of 12 articles involving 866 individuals were included, meta-analysis results suggesting that gender (OR = 0.75, 95% CI [0.51-1.10]), age (OR = 1.00, 95% CI [0.93-1.07]), aneurysm size (OR = 0.85, 95% CI [-0.71 to 1.01]), treatment time (OR = 1.01, 95% CI [0.91-1.13]) is not a risk factor for recovery of motor nerve palsy after aneurysm surgery. Preoperative complete ONP (OR = 2.27, 95% CI [1.07-4.81]), surgery (OR = 9.88, 95% CI [2.53-38.57]), subarachnoid hemorrhage (OR = 1.29, 95% CI [1.06-1.56]) is a risk factor for recovery of motor nerve palsy after aneurysm surgery.
Conclusion: Based on the results of the studies we included, we found that complete ONP before surgery led to poorer recovery, but patients with post-operative and subarachnoid hemorrhage had better recovery.
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