全球脑膜炎球菌倡议:对西欧抗生素耐药性、控制策略和宣传工作的见解。

IF 14.3 1区 医学 Q1 INFECTIOUS DISEASES Journal of Infection Pub Date : 2024-11-01 DOI:10.1016/j.jinf.2024.106335
Ray Borrow, Helen Campbell, Dominique A Caugant, Abdessalam Cherkaoui, Heike Claus, Ala-Eddine Deghmane, Ener Cagri Dinleyici, Lee H Harrison, William P Hausdorff, Paula Bajanca-Lavado, Corinne Levy, Wesley Mattheus, Claudia Mikula-Pratschke, Paula Mölling, Marco Ap Sáfadi, Vinny Smith, Nina M van Sorge, Paola Stefanelli, Muhamed-Kheir Taha, Maija Toropainen, Georgina Tzanakaki, Julio Vázquez
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引用次数: 0

摘要

在西欧,许多国家都拥有健全而完善的监测系统和病例报告机制。整个西欧的 IMD 发病率较低,以 B 型脑膜炎球菌血清群(MenB)为主。该地区的病例确认和抗菌药物药敏试验通常都是标准化的,许多国家还实施了健全的疫苗接种计划。在大多数欧洲国家,MenB 和 MenACWY 疫苗都是国家免疫计划 (NIP) 的一部分,只有瑞典在特殊情况下才提供疫苗接种。尽管制定了这些计划,但仍亟需开展宣传工作,以影响诊断、检测和治疗方面的变化。最近开展的活动,如世界脑膜炎日数字工具包,有助于提高人们对脑膜炎球菌疾病的认识和关注。人们对抗生素耐药性的认识也导致了耐抗生素脑膜炎球菌菌株的发现,整个地区的耐抗生素脑膜炎球菌菌株都在增加,尽管增幅不大。西班牙、葡萄牙、德国、瑞士和法国等国报告了对青霉素、环丙沙星耐药的菌株和/或对第三代头孢菌素敏感性降低的分离株。
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Global Meningococcal Initiative: Insights on antibiotic resistance, control strategies and advocacy efforts in Western Europe.

In Western Europe, many countries have robust and well-established surveillance systems and case reporting mechanisms. IMD incidence across Western Europe is low with a predominance of meningococcal serogroup B (MenB). Case confirmation and antimicrobial susceptibility testing is often standardised in this region, with many countries also having robust vaccination programmes in place. Both MenB and MenACWY vaccines form part of National Immunisation Programmes (NIPs) in most European countries, with Sweden only offering vaccination in special circumstances. Despite these established programmes, there remains a critical need for advocacy efforts in affecting change in diagnosis, testing, and treatment. Recent campaigns, such as the World Meningitis Day digital toolkit, have helped raise awareness and draw attention to meningococcal disease. Awareness around antibiotic resistance has also led to the identification of antibiotic-resistant meningococcal strains, with an increase, albeit small, in these strains noted across the region. Countries such as Spain, Portugal, Germany, Switzerland, and France have either reported strains resistant to penicillin, ciprofloxacin and/or isolates with a reduced susceptibility to third-generation cephalosporins.

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来源期刊
Journal of Infection
Journal of Infection 医学-传染病学
CiteScore
45.90
自引率
3.20%
发文量
475
审稿时长
16 days
期刊介绍: The Journal of Infection publishes original papers on all aspects of infection - clinical, microbiological and epidemiological. The Journal seeks to bring together knowledge from all specialties involved in infection research and clinical practice, and present the best work in the ever-changing field of infection. Each issue brings you Editorials that describe current or controversial topics of interest, high quality Reviews to keep you in touch with the latest developments in specific fields of interest, an Epidemiology section reporting studies in the hospital and the general community, and a lively correspondence section.
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