过敏性鼻炎免疫疗法的最新进展。

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL World Journal of Clinical Cases Pub Date : 2024-11-06 DOI:10.12998/wjcc.v12.i31.6451
Yu Fu, Yi-Lai Song, Zhong-Guo Liu
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引用次数: 0

摘要

过敏性鼻炎(AR)给全球健康造成了巨大负担,有可能发展成哮喘,从而影响患者的生活质量。免疫疗法通过改变过敏性鼻炎的潜在疾病机制,在减轻临床症状方面已显示出疗效。本文全面回顾了 AR 免疫疗法的现状,涵盖了免疫治疗策略的各个方面,阐明了其机制和临床意义。通过对 AR 免疫疗法现状的细致了解,本综述旨在为临床治疗策略提供有价值的参考。随后对各种免疫治疗途径进行了分析,以全面了解其机制和临床意义。本综述对皮下免疫疗法、舌下免疫疗法、口服免疫疗法、淋巴内免疫疗法以及创新的金诱导自体血清静脉注射疗法进行了细致的研究。对每种途径都进行了系统阐述,并强调了其在管理 AR 方面的显著特点和潜在贡献。总之,综合流行病学的见解、免疫疗法的细微差别以及针对特定途径的分析,我们对 AR 的免疫疗法有了深刻的了解。
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Recent developments in immunotherapy approaches for allergic rhinitis.

Allergic rhinitis (AR) poses a significant global health burden, with the potential to progress to asthma, thereby impacting patients' quality of life. Immunotherapy has demonstrated effectiveness in mitigating clinical symptoms by altering the underlying disease mechanisms of AR. This article provides a thorough review of the current state of immunotherapy for AR, encompassing various facets of immunotherapeutic strategies, elucidating their mechanisms and clinical implications. By presenting a nuanced understanding of the present landscape of immunotherapy for AR, this review aims to serve as a valuable reference for informing clinical treatment strategies. The subsequent analysis of diverse immunotherapeutic pathways offers a comprehensive understanding of their mechanisms and clinical implications. A meticulous examination is conducted on subcutaneous immunotherapy, sublingual immunotherapy, oral immunotherapy, intralymphatic immunotherapy, and innovative intravenous gold-induced autologous serum injection therapy. Each pathway is systematically elucidated, with its distinctive features and potential contributions to managing AR emphasized. In conclusion, synthesizing epidemiological insights, immunotherapeutic nuances, and pathway-specific analyses encapsulates a profound understanding of immunotherapy for AR.

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来源期刊
World Journal of Clinical Cases
World Journal of Clinical Cases Medicine-General Medicine
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3384
期刊介绍: The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.
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