HNSCC和LUSC中TRA2B基因遗传改变和表达谱的相关性。

Q4 Dentistry Folia medica Pub Date : 2024-10-31 DOI:10.3897/folmed.66.e117367
Amba Esakki, Anitha Pandi, Smiline A S Girija, Vijayashree Priyadharsini Jayaseelan
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引用次数: 0

摘要

引言变形蛋白(TRA2B)是一个丝氨酸/富精氨酸(SR)类蛋白家族,它以浓度依赖性方式调节多个基因的替代剪接。编码 TRA2B 的 TRA2B 基因的扩增发生在多种恶性肿瘤中,包括肺癌、宫颈癌、头颈癌、卵巢癌、胃癌和子宫癌。
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Correlating the genetic alterations and expression profile of the TRA2B gene in HNSCC and LUSC.

Introduction: Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine.

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来源期刊
Folia medica
Folia medica Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
121
审稿时长
5 weeks
期刊最新文献
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