点阵消融激光疗法在创伤疤痕治疗中对功能、症状和生活质量的影响:综述。

IF 2.2 3区 医学 Q2 DERMATOLOGY Lasers in Surgery and Medicine Pub Date : 2024-11-10 DOI:10.1002/lsm.23858
Vy X Pham, Bobak T Pousti, Gerd Gauglitz, Peter R Shumaker
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引用次数: 0

摘要

目的:大量文献探讨了点阵消融激光疗法治疗烧伤和其他创伤导致的外伤性瘢痕的安全性和有效性,而且这种疗法的范围还在不断扩大。然而,现有的疤痕研究通常采用标准化的评估量表,一般不会直接涉及对功能和整体生活质量的影响。与以往的综述不同,本稿件将探讨现有的证据,明确关注功能和生活质量(QoL)结果,而不再强调主要依赖视觉特征的替代性结果测量:通过对截至 2024 年 1 月的文献进行回顾,作者研究了以点阵消融激光疗法治疗创伤和烧伤疤痕的功能和生活质量为重点的相关研究。主要数据库包括 PubMed、EMBASE、MEDLINE 和 Cochrane Library。参考文献列表是对文献综述过程的补充。未强调功能或 QoL 终点或非英语的研究被排除在外:综述研究表明,点阵消融疗法可持续显著改善外伤性瘢痕患者的功能预后、缓解瘙痒和疼痛,并全面提高生活质量。与点阵消融疗法相关的不良事件并不常见,且一般程度较轻,这表明该疗法具有良好的安全性:本次文献综述的研究结果提供了大量现有证据,支持点阵消融疗法在增强功能、提高活动能力、减轻瘙痒和疼痛以及改善整体生活质量方面的有效性和安全性。应将点阵消融激光疗法更广泛地纳入标准管理方案。鉴于以往对标准化疤痕评估工具的依赖严重依赖视觉特征,未来的研究应优先考虑功能和 QoL 结果,以进一步推进疤痕管理方案并优化患者护理。
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Impact of Fractional Ablative Laser Therapy on Function, Symptoms, and Quality of Life in the Management of Traumatic Scars: A Review.

Objectives: A substantial and expanding body of literature addresses the safety and efficacy of fractional ablative laser therapy for traumatic scarring resulting from burns and other trauma. However, available scar research commonly employs standardized assessment scales that generally do not directly address the impact on function and overall quality of life. Unlike past reviews, this manuscript will explore available evidence with a focus explicitly on function and quality of life (QoL) outcomes and de-emphasize surrogate outcome measures that rely primarily on visual characteristics.

Methods: Through literature review conducted up to January 2024, the authors examined relevant studies focusing on function and quality of life outcomes in traumatic and burn scar management with fractional ablative laser therapy. PubMed, EMBASE, MEDLINE, and Cochrane Library were utilized as primary databases. Reference lists were secondarily reviewed to supplement the literature review process. Studies that did not highlight functional or QoL endpoints or were not in the English language were excluded.

Results: The reviewed studies demonstrated that fractional ablative therapy led to consistent significant and meaningful improvements in functional outcomes, relief from pruritus and pain, and overall enhancements in quality of life for patients with traumatic scarring. Adverse events associated with fractional ablative therapy were infrequent and generally of mild severity, indicating a favorable safety profile.

Conclusions: The findings from this literature review document ample existing evidence supporting the efficacy and safety of fractional ablative therapy to enhance function, mobility, reduce pruritus and pain, and improve overall QoL. Fractional ablative laser therapy should be integrated more widely into standard management protocols. Given the previous reliance on standardized scar assessment tools that heavily integrate visual characteristics, future studies should prioritize functional and QoL outcomes to further advance scar management protocols and optimize patient care.

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来源期刊
CiteScore
5.40
自引率
12.50%
发文量
119
审稿时长
1 months
期刊介绍: Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
期刊最新文献
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