人工智能的小步快跑:开发 JOS 心血管疾病风险应用程序,改善心血管疾病筛查。

Q4 Medicine West African journal of medicine Pub Date : 2024-11-10
A Sirisena, N Gurumdimma, D Oguche, B Okeahialam
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引用次数: 0

摘要

导言/背景:评估心血管疾病(CVD)风险是预防心脏病学所必需的。研究已将心血管疾病风险因素归入预测 ASCVD 的算法中。这些不同的评分来自于从其他人群中获得的风险方程。在我们的研究中,我们发现用我们本地概念化的设备 "腹肌计 "测量的腹部高度比既有的人体测量指数更能预测心血管疾病:因此,我们决定将其纳入风险方程,并提出一种新的算法,这种算法不需要侵入性程序产生的数据:我们对数据进行了二次分析,并利用 10 个风险因素生成了一个算法,其中之一就是我们的新人体测量指数--腹部高度(AH)。以 CIMT 为标准,动脉粥样硬化高风险的切入值为≥0.078 厘米,我们将新工具与弗雷明汉风险评分(FRS)进行了比较:根据我们的新算法,24/221(10.9%)人属于高风险,109 和 88 人分别属于低风险和中等风险。使用 FRS,218/221 属于低风险,只有 3 人属于中度和高度风险。两种风险算法都与 CIMT 确定的风险有显著相关性,但新算法的相关系数(0.448)高于 FRS 的相关系数(0.300):我们发现,以颈动脉内膜中层厚度为标准的亚临床动脉粥样硬化与我们的新 Jos App 和弗雷明汉风险评分呈显著的正相关。但有趣的是,我们的新风险评估应用程序的相关性更高。我们已将其输入智能设备,用于试点临床研究。
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BABY STEPS IN ARTIFICIAL INTELLIGENCE: DEVELOPMENT OF A JOS CARDIOVASCULAR DISEASE RISK APP TO IMPROVE SCREENING FOR CARDIOVASCULAR DISEASES.

Introduction/background: Assessing cardiovascular disease (CVD) risk is necessary in preventive cardiology. Studies have imputed CVD risk factors in algorithms to predict ASCVD. These various scores were derived from risk equations acquired from other populations. In our research, we found that abdominal height measured with our locally conceptualized appliance the Abdominometer predicted ASCVD better than established anthropometric indices.

Objectives: We, therefore, decided to build it into a risk equation and come up with a new algorithm that will not require data generated from invasive procedures.

Methods: We secondarily analysed our data and generated an algorithm utilizing 10 risk factors: one of which was our new anthropometric index of abdominal height (AH). Using the CIMT as a standard with a cut of value of ≥0.078 cm for high atherosclerotic risk we compared our new tool with the Framingham Risk Score (FRS).

Results: With our new algorithm, 24/221 (10.9%) were at high risk with 109 and 88 at low and intermediate risks respectively. Using the FRS, 218/221 were at low risk; only 3 being in the intermediate and high risk. Both risk algorithms correlated significantly with CIMT-determined risk but the correlation coefficient was more for the new (0.448) than the FRS (0.300).

Conclusions: We found that with sub-clinical atherosclerosis indexed by carotid intima-media thickness as standard, our new Jos App as well as the Framingham Risk score correlated positively and significantly. However, interestingly the level of correlation was higher with our new risk estimation App. We have input this into smart devices for pilot clinical studies.

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来源期刊
West African journal of medicine
West African journal of medicine Medicine-Medicine (all)
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