使用 PRIMO 蒙特卡洛软件对 6 MV 光子束下的 Elekta Synergy 平台直列加速器进行验证。

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Medical Physics Pub Date : 2024-07-01 Epub Date: 2024-09-21 DOI:10.4103/jmp.jmp_48_24
Jan Risty Lucido Marzon, Vernie C Convicto, Melbagrace A Lapening, Andelson L Berondo, Angelina M Bacala
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引用次数: 0

摘要

目的:目的是利用集成在PRIMO软件中的伽马指数分析工具包,验证达沃医生医院6 MV Elekta Synergy平台直列加速器的初始射束参数:在 PRIMO 软件中,使用严格的伽马指数通过率 1%/1毫米标准(GPR11),对测量和模拟的深度剂量百分比(PDD)和不同深度的横向射束剖面进行了一系列优化处理。使用 3 厘米×3 厘米、4 厘米×4 厘米、5 厘米×5 厘米和 10 厘米×10 厘米的四个区域,在一个尺寸为 16.2 厘米×16.2 厘米×30.0 厘米的水模型上计算剂量。此外,还在一个 50.0 厘米 × 50.0 厘米 × 30.0 厘米的水模型上使用了一个 20 厘米 × 20 厘米的磁场,分区尺寸为 0.2 厘米 × 0.2 厘米 × 0.2 厘米,源面距离为 100.0 厘米:在最大磁场尺寸下的PDD和光束剖面比较中,6.5 MeV初始电子束能量、0.25 MeV全宽半最大能量、0.20 cm焦斑尺寸和3°光束发散调整配置产生的GPR11值分别为94.0%和97.7%(200 mm扫描深度下的PRIMO PDD和横向光束剖面),统计不确定性为2.9%。对于较小的磁场尺寸,PDD 的 GPR11 值始终保持在 90% 以上,而 10 厘米×10 厘米和 5 厘米×5 厘米的横向光束剖面(扫描深度分别为 15 毫米和 200 毫米)的 GPR11 值分别为 80.3% 和 70.6%。在所有现场设置中,测量和模拟的 PDD 20,10 比率之间的百分比差异均不超过 2.45%:这些调整后的射束参数与 PRIMO 网站上列出的 6 MV Elekta 直列加速器的建议射束参数非常一致。
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Validation of the Elekta Synergy Platform Linac at 6 MV Photon Beam using PRIMO Monte Carlo Software.

Aims: The objective was to validate the initial beam parameters of the Davao Doctors Hospital's 6 MV Elekta Synergy Platform linac, which performs to the specification of the commissioning data per our records using the gamma-index analysis toolkit integrated inside PRIMO software.

Materials and methods: In PRIMO, a sequence of optimization processes is performed, in which the measured and simulated percent depth dose (PDD) and lateral beam profiles at various depths are compared, using the stringent gamma-index passing rate at 1%/1 mm criteria (GPR11). Using four fields of sizes 3 cm × 3 cm, 4 cm × 4 cm, 5 cm × 5 cm, and 10 cm × 10 cm, the dose is calculated on a water phantom measuring 16.2 cm × 16.2 cm × 30.0 cm. In addition, one field of size 20 cm × 20 cm is used on a 50.0 cm × 50.0 cm × 30.0 cm water phantom with a bin size of 0.2 cm × 0.2 cm × 0.2 cm at a source-surface distance of 100.0 cm.

Results: For PDD and beam profiles comparison at the largest field size, the 6.5 MeV initial electron beam energy, 0.25 MeV full-width-half-maximum energy, 0.20 cm focal spot size, and 3° beam divergence tuned configuration yield GPR11 values of 94.0% and 97.7% (PRIMO PDD and lateral beam profile at 200 mm scan depth, respectively) with a statistical uncertainty of 2.9%. For lower field sizes, the GPR11 values are consistent at more than 90% for the PDD, whereas GPR11 values of 80.3% and 70.6% for the lateral beam profiles (at 15 mm and 200 mm scan depths) at 10 cm × 10 cm and 5 cm × 5 cm, respectively. The percentage difference between the measured and simulated PDD 20,10 ratios of not more than 2.45% is observed in all field settings.

Conclusions: These tuned beam parameters are remarkably in agreement with the suggested beam parameters listed on the PRIMO website for the 6 MV Elekta linac which was optimized with a different set of measurements.

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来源期刊
Journal of Medical Physics
Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
11.10%
发文量
55
审稿时长
30 weeks
期刊介绍: JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.
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