Dr. Andreas B. Schmidt, Prof. Dr. Eduard Y. Chekmenev, Henri de Maissin, Philipp R. Groß, Stefan Petersen, Luca Nagel, Prof. Dr. Franz Schilling, Dr. Ilai Schwartz, Prof. Dr. Thomas Reinheckel, Prof. Dr. Jan-Bernd Hövener, Dr. Stephan Knecht
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引用次数: 0
摘要
代谢磁共振成像是一种功能强大的新型分子成像模式，而基于对氢的 SABRE 技术则是一种很有前景的方法，它能以高通量、低成本、最小的方法和仪器负担使代谢物超极化。Andreas B. Schmidt、Stephan Knecht 及其合作者在这篇概念文章中回顾了最近利用 SABRE 技术首次对超极化丙酮酸进行体内代谢成像的主要进展。
Front Cover: Signal Amplification by Reversible Exchange and its Translation to Hyperpolarized Magnetic Resonance Imaging in Biomedicine (Anal. Sens. 6/2024)
Metabolic MRI is a powerful new molecular imaging modality, and parahydrogen-based SABRE technology presents a promising approach to hyperpolarize metabolites with high throughput, low cost, and minimal methodological and instrumental burden. In the Concept Article by Andreas B. Schmidt, Stephan Knecht, and co-workers key advances are reviewed that have recently enabled the first in vivo metabolic imaging with hyperpolarized pyruvate using SABRE.
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