大鼠急性乙醇中毒后部分器官与肝脏的生化相关性。

Physiologie (Bucarest) Pub Date : 1988-01-01
I Boerescu, N Gheorghe, I Boroş, L Ciuntu
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引用次数: 0

摘要

用32P观察不同剂量乙醇对大鼠磷脂代谢的影响。雄性大鼠通过口服插管接受单剂量乙醇(3.5或5.8 g/kg体重量),浓度为45%。相应的对照大鼠接受等量的水。分别于2、4、6、24、48、72小时处死大鼠。肝、脑、肾和脾的反应取决于给药剂量,并随时间变化。
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Biochemical correlations between some organs and the liver after acute ethanol intoxication in rats.

The influence of different doses of ethanol on the phospholipid metabolism in rat was investigated with 32P. Male rats received by oral intubation a single intoxicating dose of ethanol (3.5 or 5.8 g/kg body wt) as a 45% solution. The corresponding control rats received an equal volume of water. The rats were killed at 2, 4, 6, 24, 48 and 72 hours. The liver, brain, kidney and spleen responses depend on the administered dose and vary with time.

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