Sensing, feeling and sentience in unicellular organisms and living cells

Cells represent the basic units of life, not only as structural building blocks, but also as cognitive agents endowed with subjective cellular feelings, sentience (consciousness), and cognitive infocomputatioal competence. Living cells act as ‘Kantian Wholes’: All of its parts exist for and by means of the whole system, allowing cells to use sentient agency for solving existential problems and evolve as living self-organizing units. Cell sentience is based on its excitable plasma membrane generating bioelectromagnetic fields that link to a whole-cell sensory architecture. This cellular sensory apparatus, termed its senome, represents the totality of cellular self-referential information obtained by cells via their sensory systems, including the subjective cellular inside and the cell’s self-referential appraisal of its external environment. The plasma membrane was ‘invented’ by the very first cells and has been uninterruptedly inherited by cells for billions of years through successive cell divisions.