具有抗菌、再矿化和自修复功能的新一代牙科修复树脂复合材料综述

IF 5.5 3区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Nanoscale Research Letters Pub Date : 2024-11-21 DOI:10.1186/s11671-024-04151-0
Jinshuang Zhang, Yujin Yang, Yaqing Chen, Xu Chen, Ang Li, Juan Wang, Daojun Shen, Shunli Zheng
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引用次数: 0

摘要

牙科修复树脂复合材料因其美观、适当的机械性能和微创的牙齿结构制备而被广泛用于修复蛀牙。然而,牙科修复用树脂复合材料仍然面临着挑战,因为二次龋坏和大量断裂导致其失效率相对较高,使用寿命较短。因此,人们开始尝试探索具有抗菌、再矿化和自愈合功能的新一代牙科修复树脂复合材料,以抑制细菌并延长修复体的使用寿命。这种新型修复复合材料可以抑制细菌活动、减少酸的产生、促进矿物质再生,并具有可再生的优势,从而实现更高的性能,这对进一步的基础和临床研究具有启发和支持作用。在这篇综述中,首先介绍了抗菌牙科修复树脂复合材料,然后介绍了具有上述两种或两种以上功能的再矿化、自修复和多功能牙科树脂复合材料。同时,我们解释了相应的牙科修复树脂复合材料的机理,并描述了它们的特点。最后,我们进行了总结并提出了展望。这篇综述将吸引该领域的研究人员和临床医生,并有助于为设计生物医学应用的新型修复树脂复合材料提供创新思路。
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A review of new generation of dental restorative resin composites with antibacterial, remineralizing and self-healing capabilities

Dental restorative resin composites are widely used to repair tooth decay owing to attractive esthetics, adequate mechanical properties and minimally invasive tooth structure preparations. Nevertheless, dental restorative resin composites still face challenges because of their relatively high failure rate and short lifespan caused by secondary caries and bulk fracture. Thus, attempts have been carried out to explore a new generation of dental restorative resin composites with antibacterial, remineralizing, and self-healing capabilities to inhibit bacteria and lengthen the lifetime of the restorations. Such novel restorative composites can inhibit bacterial activity, reduce acid production, promote mineral regeneration and present a renewable advantage to achieve a higher performance, which are inspiring and provide support for further basic and clinical research. In this review, antibacterial dental restorative resin composites are first introduced, followed by remineralizing, self-healing, and multifunctional dental resin composites with two or more of the functions mentioned above. Meanwhile, we explain the mechanism of the corresponding dental restorative resin composites and describe their characteristics. Finally, we conclude and put forward prospects. This review will attract both researchers and clinicians in this field and help to provide innovative ideas to design new restorative resin composites for biomedical applications.

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来源期刊
Nanoscale Research Letters
Nanoscale Research Letters 工程技术-材料科学:综合
CiteScore
11.30
自引率
0.00%
发文量
110
审稿时长
48 days
期刊介绍: Nanoscale Research Letters (NRL) provides an interdisciplinary forum for communication of scientific and technological advances in the creation and use of objects at the nanometer scale. NRL is the first nanotechnology journal from a major publisher to be published with Open Access.
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