在头颈癌的不同治疗技术中实施 OSL 纳米点剂量测定。

IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES Radiation protection dosimetry Pub Date : 2024-11-22 DOI:10.1093/rpd/ncae217
Ingrid M Negrete-Hernandez, Ivonne B Lozano, Jesus Roman-Lopez, Jesus I Guzman-Castañeda
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引用次数: 0

摘要

近几十年来,放射治疗领域的技术不断进步,随之出现了用于校准和调试等用途的新型剂量测定系统。但是,由于带电粒子之间不存在平衡,因此在积聚区进行测量时会增加病人治疗时的表面剂量,并产生潜在的皮肤毒性。本研究利用光刺激剂量计(nanoDot)和放射变色膜(EBT3)测量接受放疗的头颈部癌症患者的皮肤剂量。这些结果与治疗计划系统(TPS)中计算的结果进行了比较,得出 EBT3 的变化百分比从 0.30% 到 6.15%,而 nanoDot 的变化百分比从 0.51% 到 4.88%。这种差异可能是由于患者置放的可重复性造成的。因此,在临床使用中,纳米点剂量计是一种可行的体内剂量测定替代方法,可以快速验证计划系统的结果。
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Implementation of OSL nanoDot dosimetry in different treatment techniques for head and neck cancer.

In recent decades, technological advances have been made in the field of radiotherapy and with it the emergence of new dosimetric systems for their calibration and commissioning, among other uses. Such is the case of the measurement in the build-up region, where there is no charged-particle equilibrium, which is reflected in the increase in surface dose for patient treatments and potential skin toxicities as a secondary effect. This study utilizes optically stimulated dosemeters (nanoDot) and the radiochromic film (EBT3) to measure skin doses in patients with head and neck cancer who received radiotherapy. Accurately depicting 15 patients with different diagnoses from 3 linear accelerators using 3D, intensity modulated radiation therapy, or volumetric arc therapy/RapidArc technology, these results were compared with those calculated in the treatment planning system (TPS) and obtaining a percentage of variation for the EBT3 ranged from 0.30% to 6.15%, while that observed for the nanoDot was from 0.51% to 4.88%. This difference may be attributed to the reproducibility of placement in patients. Therefore, for clinical use, nanoDot dosemeters are a viable alternative for in vivo dosimetry where rapid validation of planning system results is required.

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来源期刊
Radiation protection dosimetry
Radiation protection dosimetry 环境科学-公共卫生、环境卫生与职业卫生
CiteScore
1.40
自引率
10.00%
发文量
223
审稿时长
6-12 weeks
期刊介绍: Radiation Protection Dosimetry covers all aspects of personal and environmental dosimetry and monitoring, for both ionising and non-ionising radiations. This includes biological aspects, physical concepts, biophysical dosimetry, external and internal personal dosimetry and monitoring, environmental and workplace monitoring, accident dosimetry, and dosimetry related to the protection of patients. Particular emphasis is placed on papers covering the fundamentals of dosimetry; units, radiation quantities and conversion factors. Papers covering archaeological dating are included only if the fundamental measurement method or technique, such as thermoluminescence, has direct application to personal dosimetry measurements. Papers covering the dosimetric aspects of radon or other naturally occurring radioactive materials and low level radiation are included. Animal experiments and ecological sample measurements are not included unless there is a significant relevant content reason.
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