比哈尔邦 15 岁以下儿童感染日本脑炎的流行率。

IF 2.1 4区 医学 Q3 INFECTIOUS DISEASES Diagnostic microbiology and infectious disease Pub Date : 2024-11-14 DOI:10.1016/j.diagmicrobio.2024.116579
Maneesh Kumar , Kamal Singh , Roshan Kamal Topno , Major Madhukar , Niyamat Ali Siddiqui , Sanjay Kumar Sinha , Krishna Pandey , Ganesh Chandra Sahoo
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引用次数: 0

摘要

日本脑炎(JE)是急性脑炎综合症(AES)的主要病因。虽然比哈尔邦拥有全面的 JE 数据,但就报告病例而言,它仅次于北方邦和阿萨姆邦,排名第三。我们希望确定比哈尔邦和流行区的 JE 病例发病率。在比哈尔邦的巴特那、穆扎法尔布尔和加亚,这项研究揭示了 JEV 是导致 AES 及其流行病学的主要原因之一。我们使用印度浦那 NIV 推荐的酶免疫测定法分析了 2018 年 1 月至 2022 年 12 月间送到病毒诊断实验室的 AES 患者的血液和脑脊液样本,以检测 JEV 的 IgM 抗体。我们在 2195 人中的 193 人(8.79%)中检测到了 JEV IgM。患者的人口统计学特征包括年龄、性别和居住地。大多数患者的年龄在 6-10 岁之间,发病时间在 6 月份。尽管病死率有所下降,但我们仍需要加强宣传和跨部门预防。
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Prevalence of Japanese encephalitis infection in children below 15 years’ age, Bihar
Japanese encephalitis (JE) is the leading cause of acute encephalitis syndromes (AES). Although Bihar has comprehensive data on JE, it ranks third behind Uttar Pradesh and Assam in terms of reported cases. We wanted to determine the incidence of JE cases in Bihar and the endemic districts. In Patna, Muzaffarpur and Gaya, Bihar, this study revealed that JEV is one of the major causes of AES and its epidemiology. We analyzed blood and CSF samples from AES patients delivered to a viral diagnostic laboratory between January 2018 and December 2022 for IgM antibodies against JEV using the enzyme immunoassay recommended by NIV, Pune, India. We detected JEV IgM in 193 (8.79 %) of 2195 individuals. Patient demographics included age, gender and place of residence. Most patients were 6–10 years old and had the disease in June. We need to increase awareness initiatives and cross-sector prevention despite the decline in case fatality rate.
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来源期刊
CiteScore
5.30
自引率
3.40%
发文量
149
审稿时长
56 days
期刊介绍: Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.
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