紫外光诱导α-卤代烃的P-H插入

IF 4.9 1区化学 Q1 CHEMISTRY, ORGANIC Organic Letters Pub Date : 2024-11-29 DOI:10.1021/acs.orglett.4c04049

Chenyu Liu, Yifei Zhang, Xiu Gu, Nan Huang, Min Zhang, Jun Jiang

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引用次数: 0

摘要

描述了紫外光照射下芳基卤代二嗪与h -磷氧化物的P-H插入现象。该方法为构建多种α-卤代磷氧化物提供了一种高效、直接的途径，产率（≤95%）高，是α-卤代烃在P-H插入形成C-P键的独特例子。无金属方案具有反应条件温和、原子经济性高、环境友好等优点。

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Ultraviolet-Light-Induced P–H Insertion of α-Halocarbenes

An intriguing P–H insertion of arylhalodiazirines with H-phosphorus oxides under ultraviolet-light irradiation is described. This methodology provides an efficient and straightforward route to the construction of a variety of α-halophosphorus oxides in good yields (≤95%), which represents a unique example of P–H insertion of α-halocarbenes for C–P bond formation. The metal-free protocol features the advantages of mild reaction conditions, high atom economy, and environmental friendliness.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.

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