P.Y. Le Pennec, M.T. Klein, M. Le Besnerais, G. Tsikas, F. Champomier, D. Goossens, Ph. Rouger
{"title":"针对Rh、G和LW分子的18种单克隆抗体的免疫学特性","authors":"P.Y. Le Pennec, M.T. Klein, M. Le Besnerais, G. Tsikas, F. Champomier, D. Goossens, Ph. Rouger","doi":"10.1016/S0338-4535(88)80096-5","DOIUrl":null,"url":null,"abstract":"<div><p>In this work we studied 18 monoclonal antibodies (MAB<sub>s</sub>) of various specificities directed against Rh, G and LW molecules. These antibodies were tested by agglutination techniques using a panel of human red blood cells (RBC) of common and rare phenotypes in order to:</p><ul><li><span>1.</span><span><p>Confirm their specificity</p></span></li><li><span>2.</span><span><p>Investigate their reactivity with Rh variants</p></span></li><li><span>3.</span><span><p>Determine their titres using various techniques.</p></span></li></ul></div>","PeriodicalId":101128,"journal":{"name":"Revue Fran?aise de Transfusion et Immuno-hématologie","volume":"31 2","pages":"Pages 123-131"},"PeriodicalIF":0.0000,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80096-5","citationCount":"3","resultStr":"{\"title\":\"Immunological characterization of 18 monoclonal antibodies directed against Rh, G and LW molecules\",\"authors\":\"P.Y. Le Pennec, M.T. Klein, M. Le Besnerais, G. Tsikas, F. Champomier, D. Goossens, Ph. Rouger\",\"doi\":\"10.1016/S0338-4535(88)80096-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In this work we studied 18 monoclonal antibodies (MAB<sub>s</sub>) of various specificities directed against Rh, G and LW molecules. These antibodies were tested by agglutination techniques using a panel of human red blood cells (RBC) of common and rare phenotypes in order to:</p><ul><li><span>1.</span><span><p>Confirm their specificity</p></span></li><li><span>2.</span><span><p>Investigate their reactivity with Rh variants</p></span></li><li><span>3.</span><span><p>Determine their titres using various techniques.</p></span></li></ul></div>\",\"PeriodicalId\":101128,\"journal\":{\"name\":\"Revue Fran?aise de Transfusion et Immuno-hématologie\",\"volume\":\"31 2\",\"pages\":\"Pages 123-131\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0338-4535(88)80096-5\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revue Fran?aise de Transfusion et Immuno-hématologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0338453588800965\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue Fran?aise de Transfusion et Immuno-hématologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0338453588800965","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Immunological characterization of 18 monoclonal antibodies directed against Rh, G and LW molecules
In this work we studied 18 monoclonal antibodies (MABs) of various specificities directed against Rh, G and LW molecules. These antibodies were tested by agglutination techniques using a panel of human red blood cells (RBC) of common and rare phenotypes in order to:
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