The First Case of Serogroup Y Neisseria meningitidis and An Expanded Investigation of Healthy Carriers - Shijiazhuang City, Hebei Province, China, 2023.

What is already known about this topic?: Neisseria meningitidis (Nm) is a bacterial pathogen that causes meningococcal disease. Serogroups A, B, C, W, X, and Y account for the vast majority of cases. However, invasive meningococcal disease (IMD) caused by NmY is rare in China and has been reported only in Tianjin, Guangdong, Shanghai, and Hunan provinces and cities.

What is added by this report?: This article reports the first case of NmY:cc23 meningococcal disease in Hebei Province, confirmed by metagenomic sequencing. We also present the results of expanded surveillance in the healthy population associated with the case.

What are the implications for public health practice?: NmY has caused multiple case reports across China, especially in southern cities. The first report of a serogroup Y case in Hebei Province, and the carriage rate in the healthy population, reminds us to increase public health attention on Nm. The results of this study suggest that surveillance of the Nm carriage rate among healthy carriers and serogroup changes in Nm should be strengthened.