Lorena I. Jaramillo , Jalloul Bouajila , Edwin Vera , Séverine Camy
{"title":"超临界CO2萃取等工艺参数对斜脚草（Kunth） Kuntze （sunfo）提取物收率、化学成分及生物活性的影响","authors":"Lorena I. Jaramillo , Jalloul Bouajila , Edwin Vera , Séverine Camy","doi":"10.1016/j.supflu.2024.106492","DOIUrl":null,"url":null,"abstract":"<div><div>Sunfo volatile compounds (VC) were obtained by supercritical fluid extraction (SFE). The influence of temperature (40−60) °C, particle size (0.35–1) mm, flowrate (10−20) g/min and pressure (10−60) MPa on the yield was investigated. Composition, yield, antioxidant activity (AA) and total phenolic content (TPC) were compared with ultrasound assisted extraction (UAE), hydrodistillation (HD) and Soxhlet (SX). Extraction yields and major compounds obtained were: HD: 23.7 mg/g, thymol; SX: 244 mg/g, caryophyllene; 3′-hydroxyb-naphtoflavone; UAE: 227 mg/g, carvacrol, (z)-3-(3-ethoxy-4-hydroxy-phenyl)-2-phenylacrylic acid; SFE: 38.50 mg/g, thymol, carvacrol, (+-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, 5-hydroxyflavone and icarrin. SX presented better AA (IC<sub>50-DPPH</sub> =19.60 mg/mL) followed by UAE (IC<sub>50- DPPH</sub> =48.13 mg/mL) and HD better TPC (184.07 mg GAE/g). Antifungal activity against <em>Colletotrichum musae</em>, <em>Mucor racemosus</em> and <em>Fusarium verticillioides</em> was assessed, minimal inhibitory concentration (MIC) was obtained. VC obtained had the most active antifungal activity against fungus (MIC: (400, 400, 825) mg/L).</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"218 ","pages":"Article 106492"},"PeriodicalIF":3.4000,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of process parameters on yield, chemical composition and biological activities of Clinopodium nubigenum (Kunth) Kuntze (sunfo) extracts obtained by supercritical CO2 extraction and other techniques\",\"authors\":\"Lorena I. Jaramillo , Jalloul Bouajila , Edwin Vera , Séverine Camy\",\"doi\":\"10.1016/j.supflu.2024.106492\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Sunfo volatile compounds (VC) were obtained by supercritical fluid extraction (SFE). The influence of temperature (40−60) °C, particle size (0.35–1) mm, flowrate (10−20) g/min and pressure (10−60) MPa on the yield was investigated. Composition, yield, antioxidant activity (AA) and total phenolic content (TPC) were compared with ultrasound assisted extraction (UAE), hydrodistillation (HD) and Soxhlet (SX). Extraction yields and major compounds obtained were: HD: 23.7 mg/g, thymol; SX: 244 mg/g, caryophyllene; 3′-hydroxyb-naphtoflavone; UAE: 227 mg/g, carvacrol, (z)-3-(3-ethoxy-4-hydroxy-phenyl)-2-phenylacrylic acid; SFE: 38.50 mg/g, thymol, carvacrol, (+-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, 5-hydroxyflavone and icarrin. SX presented better AA (IC<sub>50-DPPH</sub> =19.60 mg/mL) followed by UAE (IC<sub>50- DPPH</sub> =48.13 mg/mL) and HD better TPC (184.07 mg GAE/g). Antifungal activity against <em>Colletotrichum musae</em>, <em>Mucor racemosus</em> and <em>Fusarium verticillioides</em> was assessed, minimal inhibitory concentration (MIC) was obtained. VC obtained had the most active antifungal activity against fungus (MIC: (400, 400, 825) mg/L).</div></div>\",\"PeriodicalId\":17078,\"journal\":{\"name\":\"Journal of Supercritical Fluids\",\"volume\":\"218 \",\"pages\":\"Article 106492\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2024-12-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Supercritical Fluids\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0896844624003279\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Supercritical Fluids","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0896844624003279","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Influence of process parameters on yield, chemical composition and biological activities of Clinopodium nubigenum (Kunth) Kuntze (sunfo) extracts obtained by supercritical CO2 extraction and other techniques
Sunfo volatile compounds (VC) were obtained by supercritical fluid extraction (SFE). The influence of temperature (40−60) °C, particle size (0.35–1) mm, flowrate (10−20) g/min and pressure (10−60) MPa on the yield was investigated. Composition, yield, antioxidant activity (AA) and total phenolic content (TPC) were compared with ultrasound assisted extraction (UAE), hydrodistillation (HD) and Soxhlet (SX). Extraction yields and major compounds obtained were: HD: 23.7 mg/g, thymol; SX: 244 mg/g, caryophyllene; 3′-hydroxyb-naphtoflavone; UAE: 227 mg/g, carvacrol, (z)-3-(3-ethoxy-4-hydroxy-phenyl)-2-phenylacrylic acid; SFE: 38.50 mg/g, thymol, carvacrol, (+-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, 5-hydroxyflavone and icarrin. SX presented better AA (IC50-DPPH =19.60 mg/mL) followed by UAE (IC50- DPPH =48.13 mg/mL) and HD better TPC (184.07 mg GAE/g). Antifungal activity against Colletotrichum musae, Mucor racemosus and Fusarium verticillioides was assessed, minimal inhibitory concentration (MIC) was obtained. VC obtained had the most active antifungal activity against fungus (MIC: (400, 400, 825) mg/L).
期刊介绍：
The Journal of Supercritical Fluids is an international journal devoted to the fundamental and applied aspects of supercritical fluids and processes. Its aim is to provide a focused platform for academic and industrial researchers to report their findings and to have ready access to the advances in this rapidly growing field. Its coverage is multidisciplinary and includes both basic and applied topics.
Thermodynamics and phase equilibria, reaction kinetics and rate processes, thermal and transport properties, and all topics related to processing such as separations (extraction, fractionation, purification, chromatography) nucleation and impregnation are within the scope. Accounts of specific engineering applications such as those encountered in food, fuel, natural products, minerals, pharmaceuticals and polymer industries are included. Topics related to high pressure equipment design, analytical techniques, sensors, and process control methodologies are also within the scope of the journal.
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