孟加拉某三级教学医院血流感染细菌学特征及抗生素谱分析。

Mymensingh medical journal : MMJ Pub Date : 2025-01-01
K A Talha, M I Patwary, K Fatema, H Ahmad, F Selina, M S Bhuiyan, M Khatoon, G M M Islam
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摘要

血流感染(BSI)是任何医院中最具破坏性的感染,死亡率很高。金黄色葡萄球菌、凝固酶阴性葡萄球菌(con)和肠球菌是最常见的分离细菌。这是一项横断面描述性研究,于2022年10月至2023年3月在Sylhet女子医学院医院进行。总研究期为6个月。数据收集自电子病历(EMR)。在1674份血样中,315份血培养呈阳性(18.8%)。参与者的平均年龄为15.6岁,在20岁以下年龄组中频率最高。最常见的分离细菌是金黄色葡萄球菌,其次是con,对亚胺培南(89.0%)、哌拉西林和他唑巴坦(88.0%)、多西环素(81.0%)和阿米卡星(79.0%)最敏感。准确的细菌谱和抗生素谱有助于任何机构了解当前的感染模式。应根据医院的抗生素谱选择常用的经验性抗生素。
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Bacteriological Profile and Antibiogram of Blood Stream Infection in a Tertiary Teaching Hospital of Bangladesh.

Blood stream infection (BSI) is of the most devastating infection of any hospital which has a high mortality. Staphylococcus aureus, coagulase-negative staphylococci (CONS) and enterococcus species are commonest isolated bacteria. This was a cross-sectional descriptive study conducted at the Sylhet Women's Medical College Hospital from October 2022 to March 2023. Total study period was 6 months. Data were collected from electronic medical record (EMR). Out of a total 1674 blood samples 315 samples were positive for blood culture (18.8%). The mean age of the participants was 15.6 year with a highest frequency in the below 20-year age group. Staphylococcus aureus was commonest isolated bacteria followed by CONS. Imipenem (89.0%), Piperacillin and Tazobactam (88.0%), Doxycycline (81.0%) and Amikacin (79.0%) were most sensitive antibiotics. Precise bacteriological profile and antibiogram is helpful for any institution to have an idea about the current infection pattern. Commonly used empirical antibiotics should be selected according to antibiogram of that particular hospital.

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