儿童季节性嗜酸性粒细胞性食管炎1例。

IF 1.3 4区医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI:10.51821/87.4.12922

S Vande Velde, J Willekens, R De Bruyne, P De Bruyne, S Van Biervliet

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引用次数: 0

摘要

嗜酸性食管炎（EoE）是一种以食道嗜酸性炎症为特征的慢性疾病，由食物过敏原和可能的空气过敏原引起。我们提出一个4岁的男孩诊断为EoE，该疾病对局部类固醇有反应。当他7岁时，他被诊断为草花粉过敏。组织学(2019年10月：嗜酸性粒细胞（Eo's)/高倍视野（HPF）为0,2022年4月：80 Eo's/ HPF）和临床症状（2019年10月：儿科eoe症状评分（PEESS） 3/100, 2022年4月：PEESS 31/100）在冬季和春季比较时存在明显差异。该男孩目前仅在草花粉季节局部使用布地奈德。越来越多的论据支持空气过敏原是EoE的诱因。这一信息对于确定内窥镜随访的时机非常重要。考虑在过敏季节升级治疗，或在过敏季节只进行治疗可能是有益的。

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A case of paediatric seasonal eosinophilic oesophagitis.

Eosinophilic esophagitis (EoE) is a chronic disorder characterized by eosinophilic inflammation of the oesophagus triggered by food allergens and possibly aeroallergens. We present a boy with the diagnosis of EoE at the age of 4 years and the disease responded to topical steroids. When he turned 7 years old he had the concomitant diagnose of grass pollen allergy. A clear difference between both histological (October 2019: 0 eosinophils (Eo's)/High Power Field (HPF), April 2022: 80 Eo's/ HPF) and clinical signs (October 2019: pediatric eoe symptom score (PEESS) 3/100, April 2022: PEESS 31/100) is evident when comparing winter to spring. The boy is currently only using topical budesonide during grass pollen season. There are increasing arguments in favour of aeroallergens as a trigger for EoE. This information is important for determining the timing of endoscopic follow-up. And it may be beneficial to consider upgrading treatment during allergy season, or exclusively administering treatment during allergy season.

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来源期刊

Acta gastro-enterologica Belgica Medicine-Gastroenterology

CiteScore

2.30

自引率

20.00%

发文量

期刊介绍： The Journal Acta Gastro-Enterologica Belgica principally publishes peer-reviewed original manuscripts, reviews, letters to editors, book reviews and guidelines in the field of clinical Gastroenterology and Hepatology, including digestive oncology, digestive pathology, as well as nutrition. Pure animal or in vitro work will not be considered for publication in the Journal. Translational research papers (including sections of animal or in vitro work) are considered by the Journal if they have a clear relationship to or relevance for clinical hepato-gastroenterology (screening, disease mechanisms and/or new therapies). Case reports and clinical images will be accepted if they represent an important contribution to the description, the pathogenesis or the treatment of a specific gastroenterology or liver problem. The language of the Journal is English. Papers from any country will be considered for publication. Manuscripts submitted to the Journal should not have been published previously (in English or any other language), nor should they be under consideration for publication elsewhere. Unsolicited papers are peer-reviewed before it is decided whether they should be accepted, rejected, or returned for revision. Manuscripts that do not meet the presentation criteria (as indicated below) will be returned to the authors. Papers that go too far beyond the scope of the journal will be also returned to the authors by the editorial board generally within 2 weeks. The Journal reserves the right to edit the language of papers accepted for publication for clarity and correctness, and to make formal changes to ensure compliance with AGEB’s style. Authors have the opportunity to review such changes in the proofs.