确保在SARS-CoV-2危机期间用于生产洗手液的本地来源酒精的安全性:一项全面的杂质分析。

IF 0.8 Q4 PHARMACOLOGY & PHARMACY Hospital Pharmacy Pub Date : 2024-12-30 DOI:10.1177/00185787241309254
Camille Jurado, Zoubeir Ramjaun, Souleiman El Balkhi, Franck Saint-Marcoux, Mathieu Alonso, Anne Sophie Salabert, Fanny Durand, Laetitia Caturla, David Metsu, Emilie Gardes, Isabelle Quelven-Bertin, Philippe Cestac
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引用次数: 0

摘要

在2020年初的SARS-CoV-2危机期间,严重的洗手液短缺导致OMS提出了当地生产建议,邀请了各种各样的酒精生产商做出贡献。然而,并不是所有人都遵守api级酒精的强制控制。我们进行了一项研究,以确保收到的酒精的安全性,重点是甲醇和乙醛的水平。所有样品都远低于Ph. Eur指南,确认其安全使用。此外,没有检测到额外的杂质,加强了评估的洗手液的质量和安全性。在SARS-CoV-2时代稀缺的情况下,我们的研究结果突出了在当地洗手液生产过程中进行严格安全评估的重要性。
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Ensuring the Safety of Locally Sourced Alcohols for Hand Sanitizer Production During the SARS-CoV-2 Crisis: A Comprehensive Impurity Analysis.

Amid the early 2020 SARS-CoV-2 crisis, severe hand sanitizer shortages led to OMS local production recommendations, inviting a diverse array of alcohol producers to contribute. However, not all followed mandatory controls for API-grade alcohol. We conducted a study to ensure the safety of the received alcohols, focusing on methanol and acetaldehyde levels. All samples were well below Ph. Eur guidelines, affirming their safety for use. Furthermore, no additional impurities were detected, reinforcing the quality and safety of the assessed hand sanitizers. Our findings, amidst the scarcity of the SARS-CoV-2 era, highlight the importance of rigorous safety assessments during local hand sanitizer production.

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来源期刊
Hospital Pharmacy
Hospital Pharmacy PHARMACOLOGY & PHARMACY-
CiteScore
1.70
自引率
0.00%
发文量
63
期刊介绍: Hospital Pharmacy is a monthly peer-reviewed journal that is read by pharmacists and other providers practicing in the inpatient and outpatient setting within hospitals, long-term care facilities, home care, and other health-system settings The Hospital Pharmacy Assistant Editor, Michael R. Cohen, RPh, MS, DSc, FASHP, is author of a Medication Error Report Analysis and founder of The Institute for Safe Medication Practices (ISMP), a nonprofit organization that provides education about adverse drug events and their prevention.
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