1例严重硫酸铜中毒患者成功治疗后残余高血糖。

IF 4.7 3区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Zhejiang University SCIENCE B Pub Date : 2024-12-18 DOI:10.1631/jzus.B2400305
Ting Li, Yuan-Qiang Lu
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引用次数: 0

摘要

硫酸铜是实验室环境中经常使用的铜化合物,中毒的情况并不常见。美国毒物控制中心协会的国家毒物数据系统进行的一项研究发现,在一年中只有140人暴露于铜化合物中,其中5例是故意的(Gummin et al., 2023)。硫酸铜严重中毒可导致孤立性胃肠道损伤(Galust et al., 2023)、血管内溶血(Adline et al., 2024)、横纹肌溶解(Richards et al., 2020)以及文献记载的其他症状。然而,目前还没有硫酸铜中毒患者出现长期无法控制的高血糖的报道。本病例研究记录了一例因故意摄入大剂量硫酸铜导致不明原因、长期、不受控制的高血糖并伴有多器官功能障碍的患者的治疗方法。本病例报告详细介绍了急性硫酸铜患者康复过程中的长期并发症,强调了持续监测和干预的重要性。
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Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning.

Copper sulfate is a frequently used copper compound in laboratory settings, with instances of poisoning being uncommon. A study conducted by the American Association of Poison Control Centers' National Poison Data System found that only 140 individuals were exposed to copper compounds over the course of a year, with five cases being intentional (Gummin et al., 2023). Severe poisoning from copper sulfate can result in isolated gastrointestinal injury (Galust et al., 2023), intravascular hemolysis (Adline et al., 2024), rhabdomyolysis (Richards et al., 2020), and other symptoms documented in the literature. However, there have been no reports of long-term uncontrolled hyperglycemia in patients with copper sulfate poisoning. This case study documents the treatment approach for a patient with unexplained, long-term, uncontrolled hyperglycemia, alongside multiple organ dysfunction resulting from intentional ingestion of a large dose of copper sulfate. This case report details the long-term complications in a patient's recovery from acute copper sulfate, highlighting the significance of ongoing monitoring and intervention.

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来源期刊
Journal of Zhejiang University SCIENCE B
Journal of Zhejiang University SCIENCE B 生物-生化与分子生物学
CiteScore
8.70
自引率
13.70%
发文量
2125
审稿时长
3.0 months
期刊介绍: Journal of Zheijang University SCIENCE B - Biomedicine & Biotechnology is an international journal that aims to present the latest development and achievements in scientific research in China and abroad to the world’s scientific community. JZUS-B covers research in Biomedicine and Biotechnology and Biochemistry and topics related to life science subjects, such as Plant and Animal Sciences, Environment and Resource etc.
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