Mehdi Ghaffari Sarghein, Mahdieh Abbasalizad Farhangi, Negin Nikrad
{"title":"营养充足比（NAR）能预测肥胖人群的代谢特征和血糖状态吗？","authors":"Mehdi Ghaffari Sarghein, Mahdieh Abbasalizad Farhangi, Negin Nikrad","doi":"10.1177/11786388241309847","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Metabolic syndrome (MetS) is defined as the existence of metabolic profile risk factors and impaired glycemic status such as dysglycemia, hyperinsulinemia, insulin resistance (IR), dyslipidemia, and hypertension. Several studies demonstrated that a diet that promotes proper nutritional intake; plays a critical role in the prevention and control of MetS. Our goal for conducting this cross-sectional study was to investigate any potential relationships between the nutrient adequacy ratio (NAR) and cardiometabolic risk variables within obese individuals. individuals.</p><p><strong>Methods: </strong>In the present cross-sectional study, 338 seemingly healthy participants who were overweight or obese were enrolled. The assessment of dietary consumption was conducted through a validated questionnaire comprising 168 items Then NAR was calculated for all ten vitamins and six minerals. Biochemical variables are measured by the method of enzyme-linked immunosorbent assay (ELISA). Also, LDL-C (low-density lipoprotein-cholesterol), QUICKI (quantitative insulin-sensitivity check index), and HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) were calculated using the suggested formulas.</p><p><strong>Results: </strong>Subjects in the upper NAR tertiles exhibited a significantly higher percentage of fat-free mass (<i>P</i> = .002), appetite (<i>P</i> = .002), and basal metabolic rate (BMR) (<i>P</i> = .002). In addition, Participants in the upper tertiles of NAR consumed a greater amount of energy and all vitamins and minerals included in NAR and meat, fish and poultry (MFP) (<i>P</i> < .001) as well as cholesterol, monounsaturated fatty acid (MUFA), and polyunsaturated fatty acid (PUFA) (<i>P</i> < .05). Furthermore, no association was shown between NAR and metabolic profile and glycemic status.</p><p><strong>Conclusion: </strong>According to our findings, a higher nutrient adequacy ratio (NAR) was associated with higher fat-free mass but no significant link between NAR and metabolic profile risk factors was observed.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"18 ","pages":"11786388241309847"},"PeriodicalIF":2.3000,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694301/pdf/","citationCount":"0","resultStr":"{\"title\":\"Does the Nutrient Adequacy Ratio (NAR) Predict Metabolic Profile and Glycemic Status Among the Obese Population?\",\"authors\":\"Mehdi Ghaffari Sarghein, Mahdieh Abbasalizad Farhangi, Negin Nikrad\",\"doi\":\"10.1177/11786388241309847\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Metabolic syndrome (MetS) is defined as the existence of metabolic profile risk factors and impaired glycemic status such as dysglycemia, hyperinsulinemia, insulin resistance (IR), dyslipidemia, and hypertension. Several studies demonstrated that a diet that promotes proper nutritional intake; plays a critical role in the prevention and control of MetS. Our goal for conducting this cross-sectional study was to investigate any potential relationships between the nutrient adequacy ratio (NAR) and cardiometabolic risk variables within obese individuals. individuals.</p><p><strong>Methods: </strong>In the present cross-sectional study, 338 seemingly healthy participants who were overweight or obese were enrolled. The assessment of dietary consumption was conducted through a validated questionnaire comprising 168 items Then NAR was calculated for all ten vitamins and six minerals. Biochemical variables are measured by the method of enzyme-linked immunosorbent assay (ELISA). Also, LDL-C (low-density lipoprotein-cholesterol), QUICKI (quantitative insulin-sensitivity check index), and HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) were calculated using the suggested formulas.</p><p><strong>Results: </strong>Subjects in the upper NAR tertiles exhibited a significantly higher percentage of fat-free mass (<i>P</i> = .002), appetite (<i>P</i> = .002), and basal metabolic rate (BMR) (<i>P</i> = .002). In addition, Participants in the upper tertiles of NAR consumed a greater amount of energy and all vitamins and minerals included in NAR and meat, fish and poultry (MFP) (<i>P</i> < .001) as well as cholesterol, monounsaturated fatty acid (MUFA), and polyunsaturated fatty acid (PUFA) (<i>P</i> < .05). Furthermore, no association was shown between NAR and metabolic profile and glycemic status.</p><p><strong>Conclusion: </strong>According to our findings, a higher nutrient adequacy ratio (NAR) was associated with higher fat-free mass but no significant link between NAR and metabolic profile risk factors was observed.</p>\",\"PeriodicalId\":19396,\"journal\":{\"name\":\"Nutrition and Metabolic Insights\",\"volume\":\"18 \",\"pages\":\"11786388241309847\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-01-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694301/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrition and Metabolic Insights\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/11786388241309847\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition and Metabolic Insights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/11786388241309847","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
Does the Nutrient Adequacy Ratio (NAR) Predict Metabolic Profile and Glycemic Status Among the Obese Population?
Background: Metabolic syndrome (MetS) is defined as the existence of metabolic profile risk factors and impaired glycemic status such as dysglycemia, hyperinsulinemia, insulin resistance (IR), dyslipidemia, and hypertension. Several studies demonstrated that a diet that promotes proper nutritional intake; plays a critical role in the prevention and control of MetS. Our goal for conducting this cross-sectional study was to investigate any potential relationships between the nutrient adequacy ratio (NAR) and cardiometabolic risk variables within obese individuals. individuals.
Methods: In the present cross-sectional study, 338 seemingly healthy participants who were overweight or obese were enrolled. The assessment of dietary consumption was conducted through a validated questionnaire comprising 168 items Then NAR was calculated for all ten vitamins and six minerals. Biochemical variables are measured by the method of enzyme-linked immunosorbent assay (ELISA). Also, LDL-C (low-density lipoprotein-cholesterol), QUICKI (quantitative insulin-sensitivity check index), and HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) were calculated using the suggested formulas.
Results: Subjects in the upper NAR tertiles exhibited a significantly higher percentage of fat-free mass (P = .002), appetite (P = .002), and basal metabolic rate (BMR) (P = .002). In addition, Participants in the upper tertiles of NAR consumed a greater amount of energy and all vitamins and minerals included in NAR and meat, fish and poultry (MFP) (P < .001) as well as cholesterol, monounsaturated fatty acid (MUFA), and polyunsaturated fatty acid (PUFA) (P < .05). Furthermore, no association was shown between NAR and metabolic profile and glycemic status.
Conclusion: According to our findings, a higher nutrient adequacy ratio (NAR) was associated with higher fat-free mass but no significant link between NAR and metabolic profile risk factors was observed.
期刊介绍：
Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.
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