Enhance Anti-obesity Effect of Natural Compounds through Carrier Mediation.

Obesity is a global public health problem that can lead to many health complications or comorbidities. Medication alone or in combination with lifestyle changes or surgery is the main way to combat obesity and its complications. Most anti-obesity drugs are limited by their bioavailability, target-specific, and potentially toxic effects, so there is an urgent need for alternative treatments. Based on the new revelation of the pathogenesis of obesity, as well as the efforts of multidisciplinary integration of materials, some emerging obesity treatment strategies are gradually entering the field of preclinical and clinical research. By analyzing the current status and challenges of natural compounds in obesity treatment, this review systematically summarizes the advanced functions and prospects of carrier delivery of natural ingredients in targeted delivery of obesity, as well as their application in obesity treatment. Finally, on the basis of systematic analysis of anti-obesity, the future prospects and challenges in this field are put forward.