A Case of Ramipril-Induced Angioedema and Solar Purpura.

Abstract: This case report describes a patient who developed solar purpura after treatment for angioedema associated with ramipril, an angiotensin-converting enzyme inhibitor. The patient presented to the ED with angioedema. She had been using ramipril for 2 years. Two days after she was admitted, a malar "butterfly" rash occurred on her face and purpura on her lower lip and chin, as well as the extensor part of her forearm. After testing and review of the patient history, she was diagnosed with solar purpura and began topical corticosteroid and antiscar cream treatment. The patient's lesions healed with an atrophic scar in 3 weeks. To the authors' knowledge, this is the first such case to be reported in the literature.