影响西藏大学生乙肝疫苗接种意愿和行为的因素:来自扩展计划行为理论的启示

IF 4.1 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Human Vaccines & Immunotherapeutics Pub Date : 2025-12-01 Epub Date: 2025-01-16 DOI:10.1080/21645515.2025.2452026
Qi Chen, Jun Ma, Ruipeng Wu, Yingting Wang, Xiaoxin Ma, Xiaolei Zheng, Hui Jin
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引用次数: 0

摘要

乙型肝炎(heb)仍然是全球范围内一个重要的公共卫生问题,特别是在西藏,在那里,大学生的疫苗接种率和影响因素尚未得到充分研究。本研究采用横断面设计对西藏地区1126名大学生乙肝疫苗接种率进行调查,并运用扩展计划行为理论(ETPB)识别疫苗接种行为意向(BI)和疫苗接种行为(VB)。采用分层整群抽样方法对三所高校的行为态度(BA)、主观规范(SN)、感知行为控制(PBC)、既往疫苗接种史(PVH)和疫苗接种知识(VK)进行评估,并采用结构方程模型(SEM)进行模型验证和多组比较。结果显示,16.3%的学生接种了乙肝疫苗。VK明显改善BA对疫苗接种(β= 0.518,pβ= 0.232,pβ= 0.239,pβ= 0.385,pβ= 0.448,pβ= 0.127,pβ= 0.151,pβ= 0.076,pβ= 0.503,pβ= 0.366,p
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Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior.

Hepatitis B (Hep B) remains a critical public health issue globally, particularly in Tibet, where vaccination rates and influencing factors among college students are yet understudied. This study applies a cross-sectional design to investigate the Hep B vaccination rate among 1,126 college students in Tibet and utilizes the expanded theory of planned behavior (ETPB) to identify vaccination behavior intention (BI) and vaccination behavior (VB). Stratified cluster sampling across three universities was used to assess behavioral attitudes (BA), subjective norms (SN), perceived behavioral control (PBC), past vaccination history (PVH) and vaccination knowledge (VK), and used structural equation modeling (SEM) for model validation and multi-group comparison. Results indicated that 16.3% of students had received the Hep B vaccine. VK notably improved BA toward vaccination (β = 0.518, p < .001). BA (β = 0.232, p < .001), PBC (β = 0.239, p < .001), SN (β = 0.385, p < .001) positively influenced BI. However, PVH failed to predict BI. BI (β = 0.448, p < .001) and PVH (β = 0.127, p < .001) were significant predictors of VB. Significant ethnic variations were noted. The positive effect of PVH on VB (β = 0.151, p < .001) and the mediating role of PBC in VB (β = 0.076, p < .05) were significant among Tibetan students. The effect of VK on BA was stronger among Tibetans (β = 0.503, p < .05),while the impact of attitude on BI was more pronounced among Han students (β = 0.366, p < .05). The vaccination rate for Hep B among college students in Tibet is relatively low, and the ETPB model effectively explains their vaccination intentions and behaviors. Tailored intervention strategies for Tibetan and Han students are recommended to boost vaccination rates effectively.

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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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