Ting Zhang , Rui Zhang , Yunyang Zhang , Perumal Ramesh Kannan , Yao Li , Yudie Lv , Ruibo Zhao , Xiangdong Kong
{"title":"组织工程用丝基生物材料。","authors":"Ting Zhang , Rui Zhang , Yunyang Zhang , Perumal Ramesh Kannan , Yao Li , Yudie Lv , Ruibo Zhao , Xiangdong Kong","doi":"10.1016/j.cis.2025.103413","DOIUrl":null,"url":null,"abstract":"<div><div>Tissue engineering (TE) involves repairing, replacing, regeneration, or improving the function of tissues and organs by combining cells, growth factors and scaffold materials. Among these, scaffold materials play a crucial role. Silk fibroin (SF), a natural biopolymer, has been widely used in the TE field due to its good biodegradability, biocompatibility, and mechanical properties attributed to its chemical composition and structure. This paper reviews the structure, extraction, and modification methods of SF. In addition, it discusses SF's regulation of cell behavior and its various processing modes. Finally, the applications of SF in TE and perspectives on future developments are presented. This review provides comprehensive and alternative rational insights for further biomedical translation in SF medical device design, further revealing the great potential of SF biomaterials.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"338 ","pages":"Article 103413"},"PeriodicalIF":19.3000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Silk-based biomaterials for tissue engineering\",\"authors\":\"Ting Zhang , Rui Zhang , Yunyang Zhang , Perumal Ramesh Kannan , Yao Li , Yudie Lv , Ruibo Zhao , Xiangdong Kong\",\"doi\":\"10.1016/j.cis.2025.103413\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Tissue engineering (TE) involves repairing, replacing, regeneration, or improving the function of tissues and organs by combining cells, growth factors and scaffold materials. Among these, scaffold materials play a crucial role. Silk fibroin (SF), a natural biopolymer, has been widely used in the TE field due to its good biodegradability, biocompatibility, and mechanical properties attributed to its chemical composition and structure. This paper reviews the structure, extraction, and modification methods of SF. In addition, it discusses SF's regulation of cell behavior and its various processing modes. Finally, the applications of SF in TE and perspectives on future developments are presented. This review provides comprehensive and alternative rational insights for further biomedical translation in SF medical device design, further revealing the great potential of SF biomaterials.</div></div>\",\"PeriodicalId\":239,\"journal\":{\"name\":\"Advances in Colloid and Interface Science\",\"volume\":\"338 \",\"pages\":\"Article 103413\"},\"PeriodicalIF\":19.3000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Colloid and Interface Science\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0001868625000247\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Colloid and Interface Science","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0001868625000247","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/27 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Tissue engineering (TE) involves repairing, replacing, regeneration, or improving the function of tissues and organs by combining cells, growth factors and scaffold materials. Among these, scaffold materials play a crucial role. Silk fibroin (SF), a natural biopolymer, has been widely used in the TE field due to its good biodegradability, biocompatibility, and mechanical properties attributed to its chemical composition and structure. This paper reviews the structure, extraction, and modification methods of SF. In addition, it discusses SF's regulation of cell behavior and its various processing modes. Finally, the applications of SF in TE and perspectives on future developments are presented. This review provides comprehensive and alternative rational insights for further biomedical translation in SF medical device design, further revealing the great potential of SF biomaterials.
期刊介绍：
"Advances in Colloid and Interface Science" is an international journal that focuses on experimental and theoretical developments in interfacial and colloidal phenomena. The journal covers a wide range of disciplines including biology, chemistry, physics, and technology.
The journal accepts review articles on any topic within the scope of colloid and interface science. These articles should provide an in-depth analysis of the subject matter, offering a critical review of the current state of the field. The author's informed opinion on the topic should also be included. The manuscript should compare and contrast ideas found in the reviewed literature and address the limitations of these ideas.
Typically, the articles published in this journal are written by recognized experts in the field.
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