药物相关大疱性类天疱疮:有什么新进展?

IF 2.6 4区 医学 Q3 DERMATOLOGY Italian Journal of Dermatology and Venereology Pub Date : 2024-12-01 DOI:10.23736/S2784-8671.24.07907-6
Efthymia Soura, Maria Gerochristou, Theodora Douvali, Vassiliki Chasapi, Alexander Stratigos
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引用次数: 0

摘要

大疱性类天疱疮(BP)被认为是影响皮肤最常见的自身免疫性疾病之一。药物相关性血压(DABP)是由摄入特定类型的药物引起的血压的一个子集。到目前为止,已有超过80种药物与这种情况有关,直到最近才开始得到更好的描述。与特发性BP相比,DABP具有更好的临床病程和预后,特别是在及时停用疑似煽动性药物的情况下。因此,从BP患者那里获得详细的病史非常重要,尤其是在接受多种药物治疗的情况下,同时也要警惕组织病理学、ELISA和免疫荧光结果中的细微但重要的适应症以及该疾病的临床表现。
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Drug associated bullous pemphigoid: what's new?

Bullous pemphigoid (BP) is considered to be one of the most common autoimmune diseases affecting the skin. Drug associated BP (DABP) is a subset of BP that is caused by the ingestion of specific types of medications. Until this point more than 80 medications have been associated with this condition that only recently has started to be better described. DABP has a better clinical course and prognosis compared to that of idiopathic BP, especially when the suspected inciting medication is discontinued in a timely manner. Therefore, it is very important to obtain detailed medical histories from BP patients especially if they are receiving multiple medications and also to be vigilant for subtle, but important, indications in histopathological, ELISA and immunofluorescence findings as well as in the clinical manifestations of the disorder.

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