无催化剂条件下重氮盐合成6-氨基尿嘧啶n -苯偶氮（三嗪）衍生物

IF 2.7 4区化学 Q1 CHEMISTRY, ORGANIC Asian Journal of Organic Chemistry Pub Date : 2024-10-18 DOI:10.1002/ajoc.202400409

Shikha Pandey, Arsala Kamal, Ambuj Kumar Kushwaha, Dr. Sundaram Singh

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引用次数: 0

摘要

本研究首次以吡啶为原料，在室温下无催化剂条件下制备了6-氨基嘧啶化合物的n -苯基偶氮（三嗪）衍生物，工艺简单、高效、绿色。这种方法的主要优点是不需要催化剂，价格低廉，环保，无毒，操作简单。该技术显示了尿嘧啶化合物和重氮盐的广泛底物相容性。

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Synthesis of N-Phenylazo (Triazine) Derivatives of 6-Aminouracil Using Diazonium Salt Under Catalyst-Free Condition

In the current study, for the first time, N-phenylazo (triazine) derivatives of 6-aminouracil compounds were produced at room temperature under catalyst-free conditions in pyridine using an easy, efficient, and green process. The main advantages of this approach are that it doesn't require a catalyst, is inexpensive, eco-friendly, non-toxic, and simple to handle. This technique shows a broad range of substrate compatibility for uracil compounds and diazonium salts.

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.