{"title":"中药序贯疗法治疗非酒精性脂肪肝的疗效观察。","authors":"Li Zhang, Yuanfang Qian, Hongdi Wu, Hongyan Xu","doi":"10.12669/pjms.41.2.11352","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Sequential therapy in traditional Chinese medicine (TCM) refers to a combination of internal and external treatment methods in a certain order based on syndrome differentiation and therapy. The aim of this study was to evaluate the efficacy of TCM sequential therapy that is given on the basis of conventional management in patients with non-alcoholic fatty liver disease (NAFLD).</p><p><strong>Methods: </strong>Medical records of one hundred NAFLD patients who received treatment at Zhejiang Provincial Tongde Hospital between February 2023 and April 2024 were retrospectively analyzed. Of them, 48 patients received routine intervention (Control group), and 52 patients were additionally treated by sequential TCM therapy (TCM group). The levels of blood lipid indicators, liver function indicators, TCM syndrome efficacy, and quality of life (QOL) scores were compared between the two groups before and after the intervention.</p><p><strong>Results: </strong>After the intervention, the levels of blood lipid and liver function indicators in both groups were significantly improved compared to preintervention and were considerably better in the TCM compared to the Control group (<i>P</i><0.05). The overall efficacy was higher in the TCM group (94.23%) compared to the Control group (79.17%) (<i>P</i><0.05). After the intervention, the QOL scores of both groups increased and were significantly higher in the TCM group than in the Control group (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>For NAFLD patients, adopting TCM sequential therapy in addition to the routine disease management strategies can effectively regulate patients' blood lipid levels, restore liver function, improve disease treatment effectiveness, and improve the quality of life.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 2","pages":"512-518"},"PeriodicalIF":1.2000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11803795/pdf/","citationCount":"0","resultStr":"{\"title\":\"The efficacy of traditional Chinese medicine sequential therapy in non-alcoholic fatty liver disease.\",\"authors\":\"Li Zhang, Yuanfang Qian, Hongdi Wu, Hongyan Xu\",\"doi\":\"10.12669/pjms.41.2.11352\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Sequential therapy in traditional Chinese medicine (TCM) refers to a combination of internal and external treatment methods in a certain order based on syndrome differentiation and therapy. The aim of this study was to evaluate the efficacy of TCM sequential therapy that is given on the basis of conventional management in patients with non-alcoholic fatty liver disease (NAFLD).</p><p><strong>Methods: </strong>Medical records of one hundred NAFLD patients who received treatment at Zhejiang Provincial Tongde Hospital between February 2023 and April 2024 were retrospectively analyzed. Of them, 48 patients received routine intervention (Control group), and 52 patients were additionally treated by sequential TCM therapy (TCM group). The levels of blood lipid indicators, liver function indicators, TCM syndrome efficacy, and quality of life (QOL) scores were compared between the two groups before and after the intervention.</p><p><strong>Results: </strong>After the intervention, the levels of blood lipid and liver function indicators in both groups were significantly improved compared to preintervention and were considerably better in the TCM compared to the Control group (<i>P</i><0.05). The overall efficacy was higher in the TCM group (94.23%) compared to the Control group (79.17%) (<i>P</i><0.05). After the intervention, the QOL scores of both groups increased and were significantly higher in the TCM group than in the Control group (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>For NAFLD patients, adopting TCM sequential therapy in addition to the routine disease management strategies can effectively regulate patients' blood lipid levels, restore liver function, improve disease treatment effectiveness, and improve the quality of life.</p>\",\"PeriodicalId\":19958,\"journal\":{\"name\":\"Pakistan Journal of Medical Sciences\",\"volume\":\"41 2\",\"pages\":\"512-518\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11803795/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pakistan Journal of Medical Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12669/pjms.41.2.11352\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12669/pjms.41.2.11352","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
The efficacy of traditional Chinese medicine sequential therapy in non-alcoholic fatty liver disease.
Objective: Sequential therapy in traditional Chinese medicine (TCM) refers to a combination of internal and external treatment methods in a certain order based on syndrome differentiation and therapy. The aim of this study was to evaluate the efficacy of TCM sequential therapy that is given on the basis of conventional management in patients with non-alcoholic fatty liver disease (NAFLD).
Methods: Medical records of one hundred NAFLD patients who received treatment at Zhejiang Provincial Tongde Hospital between February 2023 and April 2024 were retrospectively analyzed. Of them, 48 patients received routine intervention (Control group), and 52 patients were additionally treated by sequential TCM therapy (TCM group). The levels of blood lipid indicators, liver function indicators, TCM syndrome efficacy, and quality of life (QOL) scores were compared between the two groups before and after the intervention.
Results: After the intervention, the levels of blood lipid and liver function indicators in both groups were significantly improved compared to preintervention and were considerably better in the TCM compared to the Control group (P<0.05). The overall efficacy was higher in the TCM group (94.23%) compared to the Control group (79.17%) (P<0.05). After the intervention, the QOL scores of both groups increased and were significantly higher in the TCM group than in the Control group (P<0.05).
Conclusions: For NAFLD patients, adopting TCM sequential therapy in addition to the routine disease management strategies can effectively regulate patients' blood lipid levels, restore liver function, improve disease treatment effectiveness, and improve the quality of life.
期刊介绍：
It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad.
Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.
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