利用受体结合蓝图加速哺乳动物丝状病毒研究

IF 18.7 1区医学 Q1 MICROBIOLOGY Cell host & microbe Pub Date : 2025-02-12 DOI:10.1016/j.chom.2025.01.006

Xinglou Yang, Sandra Chiu

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引用次数: 0

摘要

受体结合是病毒感染的第一步。在本期《细胞宿主》杂志中；Gorka等人利用机器学习进行了大规模受体结合试验，以预测易感宿主物种并指导主动监测丝状病毒。这项研究为人畜共患疾病的研究和预防提供了多学科的蓝图。

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Accelerating mammalian filovirus research with receptor binding blueprints

Receptor binding is the first step for virus infection. In this issue of Cell Host & Microbe, Gorka et al. conducted large-scale receptor binding assays with machine learning to predict susceptible host species and guide proactive filovirus surveillance. This study provides multidisciplinary blueprints for research and prevention of zoonotic disease.

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.