通过二卤代苯与硝基化合物的乌尔曼偶联合成新的苯并噻唑、苯并恶唑和苯并 [1, 3] 二硫醇--杂茂烯加合物

IF 2.5 4区化学 Q2 Engineering Chemical Papers Pub Date : 2025-01-10 DOI:10.1007/s11696-024-03878-5

Manijeh Nematpour

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引用次数: 0

摘要

本文在超声照射下，以铜催化剂Cs2CO3为底物，利用二卤苯和硝基杂苯二烯化合物的Ullman偶联反应，成功地快速、高效地合成了各种类型的苯并噻唑、苯并恶唑和苯并[1,3]-二噻唑。使用简单易得的起始材料，温和的铜催化反应条件，无需柱层析，收率高，应用声化学方法，反应时间短是该方案的显著特点。图形抽象

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Synthesis of new benzothiazoles, benzoxazoles, and benzo [1, 3]-dithiols by Ullmann coupling of dihalobenzene and nitro compounds-heterocumulene adducts

In this contribution, a simple and fast method for the synthesis of various types of benzothiazoles, benzoxazoles, and benzo[1,3]-dithioles using Ullman coupling reaction of dihalobenzene and nitro-heterocumulene compounds in the vicinity of copper catalyst, Cs₂CO₃ as the base, and highly efficient was successfully implemented without the help of an additional ligand under ultrasound irradiation. The use of simple and readily available starting materials, mild copper-catalytic reaction conditions, no column chromatography, good yields, applying the sonochemical methodology, and short reaction times are remarkable specifications of this protocol.

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来源期刊

Chemical Papers Chemical Engineering-General Chemical Engineering

CiteScore

3.30

自引率

4.50%

发文量

590

期刊介绍： Chemical Papers is a peer-reviewed, international journal devoted to basic and applied chemical research. It has a broad scope covering the chemical sciences, but favors interdisciplinary research and studies that bring chemistry together with other disciplines.