淋巴细胞活化过程中溶酶体酶的超微结构研究。

G Bou-Gharios, J Moss, D Abraham, T Partridge, I Olsen
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引用次数: 0

摘要

在静止和活化的T淋巴细胞和b淋巴细胞中,采用包埋后免疫金技术对溶酶体酶-葡糖苷酶进行超微结构定位。本研究结果显示,有丝分裂原诱导的T细胞和b细胞刺激与高尔基复合体和粗内质网中酶的数量增加有关,这些细胞器在静息淋巴细胞中很少存在。
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Ultrastructural studies of a lysosomal enzyme during lymphocyte activation.

A post-embedding immunogold technique has been used for the ultrastructural localization of a lysosomal enzyme, beta-glucuronidase, in resting and activated T- and B-lymphocytes. The results presented here show that mitogen-induced stimulation of T- and B-cells was associated with an increase in the amount of enzyme in the Golgi complex and rough endoplasmic reticulum, organelles which were rarely present in the resting lymphocytes.

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