[胃底和幽门粘膜对高浓度乙醇反应的差异]

Polskie archiwum weterynaryjne Pub Date : 1988-01-01
M Houszka
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引用次数: 0

摘要

对36只大鼠进行乙醇损伤后15 min、1、24、96 h的胃底、胃窦粘膜病变程度和范围的组织病理学形态学分析。在早期,乙醇直接影响引起的损伤强度在两部分相似。1 h后,尤其是24 h后,差异明显,且由继发性内源性因子引起。其中最重要的似乎是胃各部位对酒精刺激的血管网反应的特异性,浅表粘膜凝胶的分泌强度和组成的差异,以及一些活性物质的含量的差异。
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[Differences in the reaction of the mucosa of the gastric fundus and pylorus to high concentration of ethanol].

Histopathological morphometric analysis were made to determine the degree and extent of the stomach mucosa lesions in fundus and antrum of 36 rats after 15 min., 1, 24 and 96 hours after ethanol insult. At the early stage the intensity of the lesion caused by direct influence of ethanol was in both parts similar. Evident differences occurred after 1 hour, and especially after 24 hours, and were caused by secondary, endogenous agents. Among them the most important seems to be the specificity of the vascular net reaction to alcohol stimulus in each part of the stomach, differences in secretion intensity and composition of the superficial mucosal gel, as well as in the contents of some active substances.

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