{"title":"啉衍生物阿莫罗芬(Roche 14-4767/002)对白色念珠菌超微结构的影响。","authors":"J Müller, A Polak, R Jaeger","doi":"10.1111/j.1439-0507.1987.tb04372.x","DOIUrl":null,"url":null,"abstract":"Summary: Amorolfin (Roche 14–4767/002) is a phenylpropyl‐morpholine with a remarkable inhibitory effect on yeasts, dermatophytes, and other filamentous fungi. The pathological changes on the ultrastructure of Candida albicans blastospores produced by amorolfin are demonstrated by transmission electronmicroscopy. A comparison with untreated Candida cells as well as those treated with the imidazole compound oxiconazole was performed.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 11","pages":"528-40"},"PeriodicalIF":0.0000,"publicationDate":"1987-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb04372.x","citationCount":"15","resultStr":"{\"title\":\"The effect of the morpholine derivate amorolfin (Roche 14-4767/002) on the ultrastructure of Candida albicans.\",\"authors\":\"J Müller, A Polak, R Jaeger\",\"doi\":\"10.1111/j.1439-0507.1987.tb04372.x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary: Amorolfin (Roche 14–4767/002) is a phenylpropyl‐morpholine with a remarkable inhibitory effect on yeasts, dermatophytes, and other filamentous fungi. The pathological changes on the ultrastructure of Candida albicans blastospores produced by amorolfin are demonstrated by transmission electronmicroscopy. A comparison with untreated Candida cells as well as those treated with the imidazole compound oxiconazole was performed.\",\"PeriodicalId\":18826,\"journal\":{\"name\":\"Mykosen\",\"volume\":\"30 11\",\"pages\":\"528-40\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb04372.x\",\"citationCount\":\"15\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mykosen\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/j.1439-0507.1987.tb04372.x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mykosen","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1439-0507.1987.tb04372.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effect of the morpholine derivate amorolfin (Roche 14-4767/002) on the ultrastructure of Candida albicans.
Summary: Amorolfin (Roche 14–4767/002) is a phenylpropyl‐morpholine with a remarkable inhibitory effect on yeasts, dermatophytes, and other filamentous fungi. The pathological changes on the ultrastructure of Candida albicans blastospores produced by amorolfin are demonstrated by transmission electronmicroscopy. A comparison with untreated Candida cells as well as those treated with the imidazole compound oxiconazole was performed.
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